Curation Details
Interaction ID: IM-26659-8

Unique identifier for interactor Auniprotkb:Q9HAZ2
Unique identifier for interactor Buniprotkb:Q09028
Alternative identifier for interactor Aintact:EBI-2795620
uniprotkb:A6NHQ8
uniprotkb:B1AJP7
uniprotkb:B1AJP8
uniprotkb:B1AJP9
uniprotkb:B1WB48
uniprotkb:Q8WYJ9
uniprotkb:Q9C0I8
ensembl:ENSP00000270722.5
Alternative identifier for interactor Bintact:EBI-620823
uniprotkb:D3DPQ3
uniprotkb:B2R6G9
ensembl:ENSP00000362592.4
uniprotkb:B4DRH0
uniprotkb:P31149
uniprotkb:Q53H02
uniprotkb:Q96BV9
Aliases for Apsi-mi:prd16_human(display_long)
uniprotkb:PRDM16(gene name)
psi-mi:PRDM16(display_short)
uniprotkb:KIAA1675(gene name synonym)
uniprotkb:MEL1(gene name synonym)
uniprotkb:PFM13(gene name synonym)
uniprotkb:PR domain-containing protein 16(gene name synonym)
uniprotkb:Transcription factor MEL1(gene name synonym)
uniprotkb:PR domain zinc finger protein 16(gene name synonym)
Aliases for Bpsi-mi:rbbp4_human(display_long)
uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)
uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)
uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)
uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)
uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)
uniprotkb:RBBP4(gene name)
psi-mi:RBBP4(display_short)
uniprotkb:RBAP48(gene name synonym)
Interaction detection methodspsi-mi:"MI:0114"(x-ray crystallography)
First authorIvanochko et al. (2018)
Identifier of the publicationpubmed:30462309
imex:IM-26659
doi:10.1093/nar/gky1192
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-21004784
imex:IM-26659-8
Confidence scoreintact-miscore:0.62
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:table 1, suppl.fig. 6, suppl.fig. 7b,7d, suppl.table 4
comment:"\"To examine the structural basis of the interaction between PRDM3 and PRDM16 with RBBP4, we determined the crystal structures of full-length RBBP4 (residues 1–425) bound to human PRDM3 and PRDM16 peptides (residues 1–12) at 2.2 and 2.0 Å, respectively (Figure 5A and B; Table 1).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2018/11/23
Update date2018/12/11
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:1-12
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant