| Unique identifier for interactor A | uniprotkb:Q09028 |
| Unique identifier for interactor B | uniprotkb:Q03112 |
| Alternative identifier for interactor A | intact:EBI-620823 uniprotkb:D3DPQ3 uniprotkb:B2R6G9 ensembl:ENSP00000362592.4 uniprotkb:B4DRH0 uniprotkb:P31149 uniprotkb:Q53H02 uniprotkb:Q96BV9 |
| Alternative identifier for interactor B | intact:EBI-1384862 uniprotkb:C9JAK0 uniprotkb:Q5HYI1 uniprotkb:Q6MZS6 uniprotkb:Q8NEI5 uniprotkb:A1L4F3 uniprotkb:A8KA00 uniprotkb:B7Z8W7 uniprotkb:B7ZLQ3 uniprotkb:B7ZLQ4 uniprotkb:D3DNP7 ensembl:ENSP00000417899.1 intact:EBI-8475192 intact:MINT-8417693 uniprotkb:E7EQ57 uniprotkb:Q13465 uniprotkb:Q13466 uniprotkb:Q6FH90 uniprotkb:Q16122 uniprotkb:Q99917 |
| Aliases for A | psi-mi:rbbp4_human(display_long) uniprotkb:Retinoblastoma-binding protein 4(gene name synonym) uniprotkb:Retinoblastoma-binding protein p48(gene name synonym) uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym) uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym) uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym) uniprotkb:RBBP4(gene name) psi-mi:RBBP4(display_short) uniprotkb:RBAP48(gene name synonym) |
| Aliases for B | psi-mi:mecom_human(display_long) uniprotkb:MECOM(gene name) psi-mi:MECOM(display_short) uniprotkb:EVI1(gene name synonym) uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym) uniprotkb:MDS1(gene name synonym) uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym) uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym) uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym) uniprotkb:PRDM3(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Ivanochko et al. (2018) |
| Identifier of the publication | pubmed:30462309 imex:IM-26659 doi:10.1093/nar/gky1192 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-21005715 imex:IM-26659-15 |
| Confidence score | intact-miscore:0.65 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:suppl. fig. 3b comment:"\"To assess the potential role of the 12 aa peptide regions versus the PR domains for NuRD complex interactions, we purified proteins comprised of the first ∼200 residues of human PRDM3 and PRDM16 with and without these 12 residues and performed in vitro pull-down assays with purified recombinant RBBP4, which had the highest likelihood of interaction calculated by SAINTexpress for both full-length PRDM3 and PRDM16 among all the bait–prey interactions in our IP-MS datasets (Figure 3B and C). Recombinant RBBP4 only associated with the first ∼200 N-terminal residues of PRDM3 and PRDM16 in vitro when the first 12 amino acids were also present (Supplementary Figure S3B).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2018/11/23 |
| Update date | 2018/12/13 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | sufficient binding region:1-12 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Molecular weight estimation by staining |
| Participant identification method for interactor B | Molecular weight estimation by staining |