Curation Details
Interaction ID: IM-26659-1

Unique identifier for interactor Auniprotkb:P14404-2
Unique identifier for interactor Buniprotkb:Q09028
Alternative identifier for interactor Aintact:EBI-20976186
Alternative identifier for interactor Bintact:EBI-620823
uniprotkb:D3DPQ3
uniprotkb:B2R6G9
ensembl:ENSP00000362592.4
uniprotkb:B4DRH0
uniprotkb:P31149
uniprotkb:Q53H02
uniprotkb:Q96BV9
Aliases for Apsi-mi:p14404-2(display_long)
uniprotkb:Myelodysplasia syndrome 1 protein homolog(gene name synonym)
uniprotkb:Ecotropic virus integration site 1 protein(gene name synonym)
uniprotkb:Evi1(gene name synonym)
uniprotkb:Mds1(gene name synonym)
uniprotkb:Mecom(gene name)
psi-mi:Mecom(display_short)
uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)
uniprotkb:Prdm3(gene name synonym)
Aliases for Bpsi-mi:rbbp4_human(display_long)
uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)
uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)
uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)
uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)
uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)
uniprotkb:RBBP4(gene name)
psi-mi:RBBP4(display_short)
uniprotkb:RBAP48(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorIvanochko et al. (2018)
Identifier of the publicationpubmed:30462309
imex:IM-26659
doi:10.1093/nar/gky1192
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20976183
imex:IM-26659-1
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3c
comment:"\"We performed co-immunoprecipitation with western blot analysis to directly contrast the interaction between full-length and ΔPR Prdm3 and Prdm16 isoforms with members of the core NuRD complex. Western blot analysis confirmed that the full-length Prdm3 and Prdm16 isoforms associated with RBBP4, MTA1 and HDAC2, while associations with the ΔPR isoforms were not detected (Figure 3C).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-t47d)
taxid:9606(Homo sapiens T47D breast cancer tumour epithelial cell)
Parameters of the interaction-
Creation date2018/11/23
Update date2018/11/23
negative Boolean valuefalse
Feature(s) for interactor Agreen fluorescent protein tag:c-c
necessary binding region:1-190
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot