Curation Details
Interaction ID: IM-26655-7

Unique identifier for interactor Auniprotkb:Q9Y6Q6-2
Unique identifier for interactor Buniprotkb:Q12933
Alternative identifier for interactor Aintact:EBI-20899422
ensembl:ENSP00000269485.7
Alternative identifier for interactor Bintact:EBI-355744
uniprotkb:A8K107
uniprotkb:B4DPJ7
uniprotkb:Q7Z337
intact:EBI-1046651
ensembl:ENSP00000247668.2
uniprotkb:Q96NT2
Aliases for Apsi-mi:q9y6q6-2(display_long)
uniprotkb:Osteoclast differentiation factor receptor(gene name synonym)
uniprotkb:Receptor activator of NF-KB(gene name synonym)
uniprotkb:delta7,8,9(isoform synonym)
uniprotkb:TNFRSF11A(gene name)
psi-mi:TNFRSF11A(display_short)
uniprotkb:RANK(gene name synonym)
Aliases for Bpsi-mi:traf2_human(display_long)
uniprotkb:TRAF2(gene name)
psi-mi:TRAF2(display_short)
uniprotkb:TRAP3(gene name synonym)
uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)
uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorSirinian et al. (2018)
Identifier of the publicationpubmed:29844572
imex:IM-26655
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20899541
imex:IM-26655-7
Confidence scoreintact-miscore:0.46
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f5b
comment:"\"This interaction was further confirmed by immunofluorescence co-localization of RANK-c and TRAF2 in the cell cytoplasm of MDA-MB-231-RANK-c-expressing cells (Fig. 5b).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-mda_mb_231)
taxid:9606(Homo sapiens MDA-MB-231 breast adenocarcinoma cell)
Parameters of the interaction-
Creation date2018/11/16
Update date2018/11/20
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining