Curation Details
Interaction ID: IM-26547-9

Unique identifier for interactor Auniprotkb:Q9JLL3
Unique identifier for interactor Buniprotkb:Q9JLL3
Alternative identifier for interactor Aintact:EBI-20800437
ensembl:ENSMUSP00000106865.3
ensembl:ENSMUSP00000106867.3
uniprotkb:Q80T13
uniprotkb:Q812G3
uniprotkb:Q9JHF1
uniprotkb:Q9JJH6
uniprotkb:Q9JLL2
uniprotkb:Q9QXW7
Alternative identifier for interactor Bintact:EBI-20800437
ensembl:ENSMUSP00000106865.3
ensembl:ENSMUSP00000106867.3
uniprotkb:Q80T13
uniprotkb:Q812G3
uniprotkb:Q9JHF1
uniprotkb:Q9JJH6
uniprotkb:Q9JLL2
uniprotkb:Q9QXW7
Aliases for Apsi-mi:tnr19_mouse(display_long)
uniprotkb:Tnfrsf19(gene name)
psi-mi:Tnfrsf19(display_short)
uniprotkb:Taj(gene name synonym)
uniprotkb:Troy(gene name synonym)
uniprotkb:TRADE(gene name synonym)
uniprotkb:Toxicity and JNK inducer(gene name synonym)
Aliases for Bpsi-mi:tnr19_mouse(display_long)
uniprotkb:Tnfrsf19(gene name)
psi-mi:Tnfrsf19(display_short)
uniprotkb:Taj(gene name synonym)
uniprotkb:Troy(gene name synonym)
uniprotkb:TRADE(gene name synonym)
uniprotkb:Toxicity and JNK inducer(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorLiu et al. (2018)
Identifier of the publicationpubmed:30337686
imex:IM-26547
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20800435
imex:IM-26547-9
Confidence scoreintact-miscore:0.44
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BCompetitor
Experimental role ABait
Experimental role BUnspecified role
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f5a f5c
comment:"\"We further examined whether TROY (234–371 aa) could disrupt the interaction between TROY and RKIP. We prepared TROY (234–371 aa) protein tagged with TAT peptide. The GST-TROY-ICD and His-RKIP fusion proteins were incubated with the TAT protein (10 μM). Then, the GST pull-down assay was performed. RKIP bound to TROY was remarkably decreased when the TAT protein was applied (Fig. 5c, d), suggesting that the TAT-TROY (234–371 aa) protein can disrupt the interaction of TROY/RKIP in vitro.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2018/10/25
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:194-416
glutathione s tranferase tag:?-?
Feature(s) for interactor Btransactivating tag:?-?
binding-associated region:234-371
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot