| Unique identifier for interactor A | uniprotkb:P36888 |
| Unique identifier for interactor B | uniprotkb:Q8R4L0 |
| Alternative identifier for interactor A | intact:EBI-3946257 uniprotkb:B7ZLT7 uniprotkb:F5H0A0 uniprotkb:A0AVG9 uniprotkb:B7ZLT8 uniprotkb:Q13414 ensembl:ENSP00000241453.7 |
| Alternative identifier for interactor B | intact:EBI-20766300 ensembl:ENSMUSP00000029164.3 ensembl:ENSMUSP00000105189.4 uniprotkb:Q8VI42 uniprotkb:Q9D1Z9 uniprotkb:Q3UU74 uniprotkb:Q8C0K2 |
| Aliases for A | psi-mi:flt3_human(display_long) uniprotkb:FLK2(gene name synonym) uniprotkb:FL cytokine receptor(gene name synonym) uniprotkb:Fetal liver kinase-2(gene name synonym) uniprotkb:FLT3(gene name) psi-mi:FLT3(display_short) uniprotkb:STK1(gene name synonym) uniprotkb:Fms-like tyrosine kinase 3(gene name synonym) uniprotkb:Stem cell tyrosine kinase 1(gene name synonym) uniprotkb:CD135(gene name synonym) |
| Aliases for B | psi-mi:slap2_mouse(display_long) uniprotkb:Sla2(gene name) psi-mi:Sla2(display_short) uniprotkb:Src-like adapter protein 2(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Moharram et al. (2016) |
| Identifier of the publication | pubmed:27458164 imex:IM-26521 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-20766913 imex:IM-26521-33 |
| Confidence score | intact-miscore:0.52 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f2c comment:"\"a doubly phosphorylated peptide, pY589/pY591, showed dramatically increased affinity compared to either pY589 and pY591 alone (Figure 2B) and, similarly, mutations in these tyrosine residues significantly decreased association (Figure 2C).\"" agonist:FLT3 ligand curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9534(chlae-cos_1) taxid:9534(Chlorocebus aethiops COS-1 cells) |
| Parameters of the interaction | - |
| Creation date | 2018/09/25 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | mutation decreasing interaction strength:591-591 mutation decreasing interaction strength:589-589,591-591 mutation decreasing interaction strength:589-589 |
| Feature(s) for interactor B | flag tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |