| Unique identifier for interactor A | uniprotkb:P24604 |
| Unique identifier for interactor B | uniprotkb:P36888 |
| Alternative identifier for interactor A | intact:EBI-2642705 uniprotkb:Q9WVN1 uniprotkb:Q9R1M9 uniprotkb:Q9WVN2 uniprotkb:Q9WVN0 uniprotkb:Q9WVN3 |
| Alternative identifier for interactor B | intact:EBI-3946257 uniprotkb:B7ZLT7 uniprotkb:F5H0A0 uniprotkb:A0AVG9 uniprotkb:B7ZLT8 uniprotkb:Q13414 ensembl:ENSP00000241453.7 |
| Aliases for A | psi-mi:tec_mouse(display_long) uniprotkb:Tec(gene name) psi-mi:Tec(display_short) |
| Aliases for B | psi-mi:flt3_human(display_long) uniprotkb:FLK2(gene name synonym) uniprotkb:FL cytokine receptor(gene name synonym) uniprotkb:Fetal liver kinase-2(gene name synonym) uniprotkb:FLT3(gene name) psi-mi:FLT3(display_short) uniprotkb:STK1(gene name synonym) uniprotkb:Fms-like tyrosine kinase 3(gene name synonym) uniprotkb:Stem cell tyrosine kinase 1(gene name synonym) uniprotkb:CD135(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Moharram et al. (2016) |
| Identifier of the publication | pubmed:27458164 imex:IM-26521 |
| NCBI Taxonomy identifier for interactor A | taxid:10090(mouse) taxid:10090(Mus musculus) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-20766367 imex:IM-26521-25 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f1b comment:"\"COS-1 cells were transfected with plasmids for FLT3-WT or FLAG-tagged VAV2, SLAP2, CRK, ITK, TEC, NCK2, CRKL and empty vector. One day after transfection cells were stimulated with 100 ng/ml FL before lysis. Cell lysates were immunoprecipitated using 1 μg/ml anti-FLAG antibody and then analyzed by Western blotting. We observed a strong association of SLAP2 with ligand-stimulated FLT3 (Figure 1B). VAV2, ITK, TEC, and NCK2 displayed weaker interaction compared to that of SLAP2.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9534(chlae-cos_1) taxid:9534(Chlorocebus aethiops COS-1 cells) |
| Parameters of the interaction | - |
| Creation date | 2018/09/25 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | flag tag:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Anti tag western blot |