Curation Details
Interaction ID: IM-26521-17

Unique identifier for interactor Auniprotkb:P36888
Unique identifier for interactor Buniprotkb:Q8R4L0
Alternative identifier for interactor Aintact:EBI-3946257
uniprotkb:A0AVG9
uniprotkb:B7ZLT8
uniprotkb:Q13414
ensembl:ENSP00000241453.7
uniprotkb:B7ZLT7
uniprotkb:F5H0A0
Alternative identifier for interactor Bintact:EBI-20766300
ensembl:ENSMUSP00000029164.3
ensembl:ENSMUSP00000105189.4
uniprotkb:Q3UU74
uniprotkb:Q8C0K2
uniprotkb:Q8VI42
uniprotkb:Q9D1Z9
Aliases for Apsi-mi:flt3_human(display_long)
uniprotkb:FLK2(gene name synonym)
uniprotkb:FL cytokine receptor(gene name synonym)
uniprotkb:Fetal liver kinase-2(gene name synonym)
uniprotkb:FLT3(gene name)
psi-mi:FLT3(display_short)
uniprotkb:STK1(gene name synonym)
uniprotkb:Fms-like tyrosine kinase 3(gene name synonym)
uniprotkb:Stem cell tyrosine kinase 1(gene name synonym)
uniprotkb:CD135(gene name synonym)
Aliases for Bpsi-mi:slap2_mouse(display_long)
uniprotkb:Sla2(gene name)
psi-mi:Sla2(display_short)
uniprotkb:Src-like adapter protein 2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorMoharram et al. (2016)
Identifier of the publicationpubmed:27458164
imex:IM-26521
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20767058
imex:IM-26521-17
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2a
comment:"\"To identify the probable SLAP2 binding sites in FLT3, we used phosphopeptides corresponding to twelve FLT3 tyrosine phosphorylation sites. Multiple FLT3 phosphopeptides were able to pull-down SLAP2 from cell lysates (Figure 2A). Peptides corresponding to pY589 and pY591 displayed comparatively stronger association while other binding sites included pY599 and pY919.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2018/09/25
Update date2018/09/27
negative Boolean valuefalse
Feature(s) for interactor Aphosphorylated residue:955-955
binding-associated region:949-963
Feature(s) for interactor Bflag tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot