Curation Details
Interaction ID: IM-25807-10

Unique identifier for interactor Auniprotkb:P03120
Unique identifier for interactor Buniprotkb:Q8N1B4
Alternative identifier for interactor Aintact:EBI-1779322
uniprotkb:Q71BI4
Alternative identifier for interactor Bintact:EBI-2799833
uniprotkb:Q9NPT5
uniprotkb:Q8IUN6
uniprotkb:Q5JPA0
uniprotkb:Q53GR4
uniprotkb:Q5SQW1
uniprotkb:B0UZZ4
uniprotkb:A2BF38
uniprotkb:B4DNI9
ensembl:ENSP00000372697.4
ensembl:ENSP00000390831.2
ensembl:ENSP00000391197.2
ensembl:ENSP00000404016.2
ensembl:ENSP00000406988.2
ensembl:ENSP00000409952.2
Aliases for Apsi-mi:ve2_hpv16(display_long)
uniprotkb:E2(gene name)
psi-mi:E2(display_short)
Aliases for Bpsi-mi:vps52_human(display_long)
uniprotkb:SACM2L(gene name synonym)
uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)
uniprotkb:VPS52(gene name)
psi-mi:VPS52(display_short)
Interaction detection methodspsi-mi:"MI:0428"(imaging technique)
First authorMuller et al. (2011)
Identifier of the publicationpubmed:22761572
imex:IM-25807
doi:10.1371/journal.ppat.1002761
NCBI Taxonomy identifier for interactor Ataxid:333760(hpv16)
taxid:333760(Human papillomavirus type 16)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-13615394
imex:IM-25807-10
Confidence scoreintact-miscore:0.53
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F7A
comment:"\"Ectopically expressed VPS52 distributed in vesicles (Figure 7A). When co-expressed with 16, 18 or 39 E2, a colocalization of VPS52 and E2 proteins could be observed (Figure 7A). In addition, VPS52 vesicles concentrated in a perinuclear region specifically in the presence of 16E2, which in turn massively redistributed in these vesicles.\""
dataset:Virus - Publications including interactions involving viral proteins
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hacat)
taxid:9606(Homo sapiens HaCaT keratinocyte cell)
Parameters of the interaction-
Creation date2017/01/19
Update date2017/01/20
negative Boolean valuefalse
Feature(s) for interactor Agreen fluorescent protein tag:?-?
Feature(s) for interactor Bmcherry fluorescent protein tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag immunostaining
Participant identification method for interactor BAnti tag immunostaining