| Unique identifier for interactor A | uniprotkb:P16144 |
| Unique identifier for interactor B | uniprotkb:Q05397 |
| Alternative identifier for interactor A | intact:EBI-948678 uniprotkb:O14690 uniprotkb:O14691 uniprotkb:O15339 uniprotkb:O15340 uniprotkb:O15341 uniprotkb:Q9UIQ4 ensembl:ENSP00000200181.3 uniprotkb:A0AVL6 uniprotkb:Q0VF97 |
| Alternative identifier for interactor B | intact:EBI-702142 uniprotkb:Q14291 uniprotkb:Q9UD85 intact:EBI-11047590 uniprotkb:B4E2N6 uniprotkb:F5H4S4 ensembl:ENSP00000429474.1 ensembl:ENSP00000429911.1 uniprotkb:J3QT16 uniprotkb:Q8IYN9 |
| Aliases for A | psi-mi:itb4_human(display_long) uniprotkb:GP150(gene name synonym) uniprotkb:ITGB4(gene name) psi-mi:ITGB4(display_short) |
| Aliases for B | psi-mi:fak1_human(display_long) uniprotkb:PTK2(gene name) psi-mi:PTK2(display_short) uniprotkb:FAK(gene name synonym) uniprotkb:FAK1(gene name synonym) uniprotkb:pp125FAK(gene name synonym) uniprotkb:Protein-tyrosine kinase 2(gene name synonym) uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym) uniprotkb:Protein phosphatase 1 regulatory subunit 71(gene name synonym) uniprotkb:p125FAK(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Tai et al. (2016) |
| Identifier of the publication | pubmed:27178753 imex:IM-25611 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-12599466 imex:IM-25611-3 |
| Confidence score | intact-miscore:0.52 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f2b sf2b sf2c comment:"\"we found that b4 integrin coimmunoprecipitated with FAK from primary colon cancer tissues but not from paired samples of normal mucosa (Figs 2A and S2A). As expected, the interaction between b4 integrin and FAK was also detectable in HCT-116, SW480, Colo-205, and LoVo human colon cancer cells but not in HeLa human cervical cancer cells or nontumorigenic HEK-293 human embryonic kidney cells (Figs 2B and S2B,C).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-colon_cancer) taxid:9606(Homo sapiens colonic cancer tissue) |
| Parameters of the interaction | - |
| Creation date | 2016/11/18 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |