| Unique identifier for interactor A | uniprotkb:Q96CV9 |
| Unique identifier for interactor B | uniprotkb:Q9UHD2 |
| Alternative identifier for interactor A | intact:EBI-748974 uniprotkb:Q5T672 uniprotkb:Q5T673 uniprotkb:Q5T674 uniprotkb:Q5T675 uniprotkb:Q7LDL9 uniprotkb:Q8N562 uniprotkb:Q9UET9 uniprotkb:Q9UEV4 uniprotkb:Q9Y218 uniprotkb:B3KP00 uniprotkb:D3DRS4 uniprotkb:D3DRS8 ensembl:ENSP00000263036.3 ensembl:ENSP00000368021.3 ensembl:ENSP00000368022.3 ensembl:ENSP00000368032.2 |
| Alternative identifier for interactor B | intact:EBI-356402 intact:EBI-5773956 intact:EBI-1383470 uniprotkb:Q8IYV3 uniprotkb:Q9NUJ5 uniprotkb:A8K4S4 ensembl:ENSP00000329967.5 ensembl:ENSP00000498995.1 |
| Aliases for A | psi-mi:optn_human(display_long) uniprotkb:HYPL(gene name synonym) uniprotkb:Optic neuropathy-inducing protein(gene name synonym) uniprotkb:E3-14.7K-interacting protein(gene name synonym) uniprotkb:Huntingtin-interacting protein L(gene name synonym) uniprotkb:Huntingtin yeast partner L(gene name synonym) uniprotkb:NEMO-related protein(gene name synonym) uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym) uniprotkb:OPTN(gene name) psi-mi:OPTN(display_short) uniprotkb:FIP2(gene name synonym) uniprotkb:GLC1E(gene name synonym) uniprotkb:NRP(gene name synonym) uniprotkb:HIP7(gene name synonym) uniprotkb:Huntingtin-interacting protein 7(gene name synonym) |
| Aliases for B | psi-mi:tbk1_human(display_long) uniprotkb:TBK1(gene name) psi-mi:TBK1(display_short) uniprotkb:NAK(gene name synonym) uniprotkb:TANK-binding kinase 1(gene name synonym) uniprotkb:T2K(gene name synonym) uniprotkb:NF-kappa-B-activating kinase(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Meena et al. (2016) |
| Identifier of the publication | imex:IM-25518 pubmed:27086836 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-12521931 imex:IM-25518-1 |
| Confidence score | intact-miscore:0.93 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f2b f2c comment:"\"only a small fraction of optineurin coimmunoprecipitated with TBK1 in unstimulated HEK293-hTLR3 cells, and that binding greatly increased upon stimulation (Fig. 2B). Moreover, TBK1 bound to optineurin was activated, that is, phosphorylated on S172 (Fig. 2C).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2016/09/20 |
| Update date | 2024/11/21 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |