Curation Details
Interaction ID: IM-25319-1

Unique identifier for interactor Auniprotkb:P60709
Unique identifier for interactor Buniprotkb:P12814
Alternative identifier for interactor Aintact:EBI-353944
uniprotkb:P02570
uniprotkb:P70514
uniprotkb:P99021
uniprotkb:Q11211
uniprotkb:Q64316
uniprotkb:Q75MN2
uniprotkb:Q96B34
uniprotkb:Q96HG5
ensembl:ENSP00000494269.1
ensembl:ENSP00000494750.1
ensembl:ENSP00000495995.2
ensembl:ENSP00000501862.1
ensembl:ENSP00000502821.1
Alternative identifier for interactor Bintact:EBI-351710
uniprotkb:Q9BTN1
uniprotkb:Q1HE25
uniprotkb:B7TY16
intact:EBI-3866221
uniprotkb:B3V8S3
uniprotkb:B4DHH3
ensembl:ENSP00000193403.6
Aliases for Apsi-mi:actb_human(display_long)
uniprotkb:ACTB(gene name)
psi-mi:ACTB(display_short)
uniprotkb:Beta-actin(gene name synonym)
Aliases for Bpsi-mi:actn1_human(display_long)
uniprotkb:ACTN1(gene name)
psi-mi:ACTN1(display_short)
uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)
uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)
uniprotkb:F-actin cross-linking protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0027"(cosedimentation)
First authorMurphy et al. (2016)
Identifier of the publicationimex:IM-25319
pubmed:26879394
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-11783457
imex:IM-25319-1
Confidence scoreintact-miscore:0.43
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3b
comment:Quantification revealed that the amount of FLAG-actinin in the cytoskeletal fraction was increased for all the mutant proteins compared to wild-type actinin-1.
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2016/06/19
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bflag tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot