| Unique identifier for interactor A | uniprotkb:P01034 |
| Unique identifier for interactor B | uniprotkb:P01034 |
| Alternative identifier for interactor A | intact:EBI-948622 uniprotkb:Q6FGW9 uniprotkb:B2R5J9 ensembl:ENSP00000366124.3 ensembl:ENSP00000381446.1 ensembl:ENSP00000381448.1 uniprotkb:D3DW42 |
| Alternative identifier for interactor B | intact:EBI-948622 uniprotkb:Q6FGW9 uniprotkb:B2R5J9 ensembl:ENSP00000366124.3 ensembl:ENSP00000381446.1 ensembl:ENSP00000381448.1 uniprotkb:D3DW42 |
| Aliases for A | psi-mi:cytc_human(display_long) uniprotkb:Cystatin-3(gene name synonym) uniprotkb:Neuroendocrine basic polypeptide(gene name synonym) uniprotkb:Gamma-trace(gene name synonym) uniprotkb:Post-gamma-globulin(gene name synonym) uniprotkb:CST3(gene name) psi-mi:CST3(display_short) |
| Aliases for B | psi-mi:cytc_human(display_long) uniprotkb:Cystatin-3(gene name synonym) uniprotkb:Neuroendocrine basic polypeptide(gene name synonym) uniprotkb:Gamma-trace(gene name synonym) uniprotkb:Post-gamma-globulin(gene name synonym) uniprotkb:CST3(gene name) psi-mi:CST3(display_short) |
| Interaction detection methods | psi-mi:"MI:0020"(transmission electron microscopy) |
| First author | Sant'Anna et al. (2016) |
| Identifier of the publication | pubmed:26865059 imex:IM-25095 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-11686071 imex:IM-25095-3 |
| Confidence score | intact-miscore:0.77 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"Next, we used TEM to study the morphology of the species present at different times of aggregation (Fig. 3A). Interestingly, although Th-T binding has already leveled-off at 1 h under aggregation conditions, the great majority of the aggregated material presented an amorphous appearance and only few amyloid fibrils were observed at this time (Fig. 3A, left). The binding of Th-T to these amorphous species suggests that they already present cross-β fold able to accommodate this probe. These species are on-pathway to fibril formation since after 72 h under aggregation condition only mature fibrils were observed by TEM (Fig. 3A, right). At 24 h, it was already possible to see the presence of fibrils but small amorphous aggregates still remained (Fig. 3A, middle).\"" figure legend:f3a curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2016/04/08 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |