Curation Details
Interaction ID: IM-25073-19

Unique identifier for interactor Auniprotkb:O00560
Unique identifier for interactor Buniprotkb:Q15223
Alternative identifier for interactor Aintact:EBI-727004
uniprotkb:B4DUH3
uniprotkb:B7ZLN2
uniprotkb:B2R5Q7
ensembl:ENSP00000260130.4
ensembl:ENSP00000411771.2
uniprotkb:O43391
uniprotkb:O00173
uniprotkb:Q14CP2
Alternative identifier for interactor Bintact:EBI-1771314
ensembl:ENSP00000264025.3
uniprotkb:O75465
uniprotkb:Q2M3D3
uniprotkb:Q9HBE6
uniprotkb:Q9HBW2
Aliases for Apsi-mi:sdcb1_human(display_long)
uniprotkb:Scaffold protein Pbp1(gene name synonym)
uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)
uniprotkb:Syndecan-binding protein 1(gene name synonym)
uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)
uniprotkb:SDCBP(gene name)
psi-mi:SDCBP(display_short)
uniprotkb:MDA9(gene name synonym)
uniprotkb:SYCL(gene name synonym)
Aliases for Bpsi-mi:nect1_human(display_long)
uniprotkb:NECTIN1(gene name)
psi-mi:NECTIN1(display_short)
uniprotkb:HVEC(gene name synonym)
uniprotkb:Herpes virus entry mediator C(gene name synonym)
uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)
uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)
uniprotkb:PRR1(gene name synonym)
uniprotkb:PVRL1(gene name synonym)
uniprotkb:Poliovirus receptor-related protein 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorGarrido-Urbani et al. (2016)
Identifier of the publicationimex:IM-25073
pubmed:26787460
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-11668438
imex:IM-25073-19
Confidence scoreintact-miscore:0.65
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3a
comment:"\"To confirm that the interaction relies on the C-terminus of nectin-1 we performed co-IPs of over-expressed nectin-1 (wild-type or truncated form) and syntenin (Fig. 3). Truncation of the nectin PDZ binding motif abrogated the interaction, confirming the importance of the C-terminus for the interaction.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9534(chlae-cos_7)
taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)
Parameters of the interaction-
Creation date2016/03/29
Update date2016/03/29
negative Boolean valuefalse
Feature(s) for interactor Amyc tag:c-c
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot