Curation Details
Interaction ID: IM-25024-1

Unique identifier for interactor Auniprotkb:Q07812
Unique identifier for interactor Buniprotkb:P31749
Alternative identifier for interactor Aintact:EBI-516580
uniprotkb:P55269
uniprotkb:Q07814
uniprotkb:Q07815
uniprotkb:Q8WZ49
uniprotkb:Q9NR76
uniprotkb:Q9UQD6
uniprotkb:Q9NYG7
uniprotkb:Q9UCZ6
uniprotkb:Q9UCZ7
uniprotkb:A8K4W1
intact:EBI-8995042
ensembl:ENSP00000263262.9
Alternative identifier for interactor Bintact:EBI-296087
uniprotkb:Q9BWB6
uniprotkb:B2RAM5
ensembl:ENSP00000270202.4
ensembl:ENSP00000384293.2
ensembl:ENSP00000385326.2
ensembl:ENSP00000450688.1
ensembl:ENSP00000451166.1
ensembl:ENSP00000451828.1
ensembl:ENSP00000497822.1
ensembl:ENSP00000507879.1
uniprotkb:B7Z5R1
Aliases for Apsi-mi:bax_human(display_long)
uniprotkb:BAX(gene name)
psi-mi:BAX(display_short)
uniprotkb:BCL2L4(gene name synonym)
uniprotkb:Bcl-2-like protein 4(gene name synonym)
Aliases for Bpsi-mi:akt1_human(display_long)
uniprotkb:AKT1(gene name)
psi-mi:AKT1(display_short)
uniprotkb:PKB(gene name synonym)
uniprotkb:RAC(gene name synonym)
uniprotkb:RAC-PK-alpha(gene name synonym)
uniprotkb:Protein kinase B(gene name synonym)
uniprotkb:Proto-oncogene c-Akt(gene name synonym)
uniprotkb:Protein kinase B alpha(gene name synonym)
Interaction detection methodspsi-mi:"MI:0415"(enzymatic study)
First authorSimonyan et al. (2016)
Identifier of the publicationpubmed:26763134
imex:IM-25024
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-11600457
imex:IM-25024-1
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1a f1b
comment:"\"We used a constitutively active AKT variant carrying a double substitution T308D/S473D (called AKT DD).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2016/02/19
Update date2016/02/19
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant