| Unique identifier for interactor A | uniprotkb:Q5VY09 |
| Unique identifier for interactor B | uniprotkb:Q8N4C8-4 |
| Alternative identifier for interactor A | intact:EBI-1774000 uniprotkb:Q8WY68 uniprotkb:Q9NY49 uniprotkb:Q9NZP9 uniprotkb:B2RBV3 ensembl:ENSP00000356549.4 |
| Alternative identifier for interactor B | intact:EBI-11475194 ensembl:ENSP00000406487.3 |
| Aliases for A | psi-mi:ier5_human(display_long) uniprotkb:IER5(gene name) psi-mi:IER5(display_short) uniprotkb:PP4583(orf name) uniprotkb:SBBI48(orf name) |
| Aliases for B | psi-mi:q8n4c8-4(display_long) uniprotkb:GCK family kinase MiNK(gene name synonym) uniprotkb:MAPK/ERK kinase kinase kinase 6(gene name synonym) uniprotkb:MINK1(gene name) psi-mi:MINK1(display_short) uniprotkb:B55(gene name synonym) uniprotkb:MAP4K6(gene name synonym) uniprotkb:MINK(gene name synonym) uniprotkb:YSK2(gene name synonym) uniprotkb:ZC3(gene name synonym) uniprotkb:MINK-beta(isoform synonym) uniprotkb:Misshapen/NIK-related kinase(gene name synonym) uniprotkb:Mitogen-activated protein kinase kinase kinase kinase 6(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Kawabata et al. (2015) |
| Identifier of the publication | pubmed:26496226 imex:IM-24904 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-11475206 imex:IM-24904-7 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f3c comment:"\"The GST- 49C fusion failed to retain B55b-HA, suggesting that the N-terminal IER2 homology region is necessary for the binding. The GST-N246 fusion lacking the C-terminal 81 amino acids exhibited reduced binding ability relative to GST-FL; however, the C-terminal region itself failed to retain B55b-HA (GST-234C). The GST-ID fusion lacking the internal region of IER5 efficiently bound to B55b-HA. Therefore, binding to B55b is mediated by both the N-terminal and C-terminal regions of IER5, where the C-terminal region enhances the binding only in the presence of the N-terminal region\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hela) taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2016/01/07 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:1-156,237-327 glutathione s tranferase tag:?-? |
| Feature(s) for interactor B | ha tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |