Curation Details
Interaction ID: IM-24530-1

Unique identifier for interactor Auniprotkb:P15170-3
Unique identifier for interactor Buniprotkb:P98170
Alternative identifier for interactor Aintact:EBI-11189529
ensembl:ENSP00000398131.2
Alternative identifier for interactor Bintact:EBI-517127
uniprotkb:D3DTF2
ensembl:ENSP00000347858.3
ensembl:ENSP00000360242.3
ensembl:ENSP00000405529.2
uniprotkb:Q9NQ14
Aliases for Apsi-mi:p15170-3(display_long)
uniprotkb:GSPT1(gene name)
psi-mi:GSPT1(display_short)
uniprotkb:ERF3A(gene name synonym)
uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)
Aliases for Bpsi-mi:xiap_human(display_long)
uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)
uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)
uniprotkb:IAP-like protein(gene name synonym)
uniprotkb:XIAP(gene name)
psi-mi:XIAP(display_short)
uniprotkb:API3(gene name synonym)
uniprotkb:IAP3(gene name synonym)
uniprotkb:BIRC4(gene name synonym)
uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorHashimoto et al. (2015)
Identifier of the publicationpubmed:26172506
imex:IM-24530
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-11189517
imex:IM-24530-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1d f1e f1f
comment:As shown in Fig. 1E, only eRF3-Ca2+ but not full-length eRF3 co-precipitated XIAP. The A73G mutation of eRF3 abolished its interaction with XIAP, although the mutation did not affect the cleavage of eRF3.
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2015/09/23
Update date2015/09/23
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:73-637
flag tag:?-?
mutation disrupting interaction:73-73
Feature(s) for interactor Btandem tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot