| Unique identifier for interactor A | uniprotkb:P18084 |
| Unique identifier for interactor B | uniprotkb:Q96AC1 |
| Alternative identifier for interactor A | intact:EBI-1223434 uniprotkb:B2RD70 ensembl:ENSP00000296181.4 uniprotkb:B0LPF8 |
| Alternative identifier for interactor B | intact:EBI-4399465 uniprotkb:B5TJY2 ensembl:ENSP00000340391.3 ensembl:ENSP00000378993.2 intact:EBI-21355423 uniprotkb:Q14840 uniprotkb:Q86TY7 |
| Aliases for A | psi-mi:itb5_human(display_long) uniprotkb:ITGB5(gene name) psi-mi:ITGB5(display_short) |
| Aliases for B | psi-mi:ferm2_human(display_long) uniprotkb:FERMT2(gene name) psi-mi:FERMT2(display_short) uniprotkb:KIND2(gene name synonym) uniprotkb:MIG2(gene name synonym) uniprotkb:PLEKHC1(gene name synonym) uniprotkb:Kindlin-2(gene name synonym) uniprotkb:Mitogen-inducible gene 2 protein(gene name synonym) uniprotkb:Pleckstrin homology domain-containing family C member 1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Hu et al. (2014) |
| Identifier of the publication | pubmed:25448675 imex:IM-24273 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9843738 imex:IM-24273-7 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f2h comment:"\"we then performed a co-IP assay and found that FRMD5 promoted Kindlin 2 interaction with integrin but inhibited the interaction between Talin head and integrin (Fig. 2H and I). These findings indicated that FRMD5 interferes with the interaction of integrin cytoplasmic tails with their binding partners\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-a_549) taxid:9606(Homo sapiens A549 lung carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2014/10/09 |
| Update date | 2015/06/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | flag tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Anti tag western blot |