Curation Details
Interaction ID: IM-24160-19

Unique identifier for interactor Auniprotkb:O43295
Unique identifier for interactor Buniprotkb:P62993
Alternative identifier for interactor Aintact:EBI-368166
ensembl:ENSP00000373347.3
uniprotkb:Q8IX13
uniprotkb:Q8IZV8
Alternative identifier for interactor Bintact:EBI-401755
ensembl:ENSP00000339007.4
ensembl:ENSP00000376345.1
ensembl:ENSP00000376347.1
ensembl:ENSP00000496913.1
uniprotkb:P29354
uniprotkb:Q14450
uniprotkb:Q63057
uniprotkb:Q63059
Aliases for Apsi-mi:srgp3_human(display_long)
uniprotkb:SRGAP2(gene name synonym)
uniprotkb:SRGAP3(gene name)
psi-mi:SRGAP3(display_short)
uniprotkb:ARHGAP14(gene name synonym)
uniprotkb:KIAA0411(gene name synonym)
uniprotkb:MEGAP(gene name synonym)
uniprotkb:KIAA1156(gene name synonym)
uniprotkb:WAVE-associated Rac GTPase-activating protein(gene name synonym)
uniprotkb:Mental disorder-associated GAP(gene name synonym)
uniprotkb:Rho GTPase-activating protein 14(gene name synonym)
Aliases for Bpsi-mi:grb2_human(display_long)
uniprotkb:GRB2(gene name)
psi-mi:GRB2(display_short)
uniprotkb:ASH(gene name synonym)
uniprotkb:Adapter protein GRB2(gene name synonym)
uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)
uniprotkb:Protein Ash(gene name synonym)
Interaction detection methodspsi-mi:"MI:0065"(isothermal titration calorimetry)
First authorWuertenberger et al. (2015)
Identifier of the publicationimex:IM-24160
pubmed:25819436
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-10819956
imex:IM-24160-19
Confidence scoreintact-miscore:0.54
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2b f3f t2
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkd:17.0x10^-6(molar)
Creation date2015/05/12
Update date2015/05/15
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:1047-1079
mutation disrupting interaction:1056-1056,1059-1059
Feature(s) for interactor Bbinding-associated region:156-217
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant