Curation Details
Interaction ID: IM-24144-7

Unique identifier for interactor Auniprotkb:P04637
Unique identifier for interactor Buniprotkb:Q9Y618
Alternative identifier for interactor Aintact:EBI-366083
uniprotkb:Q15086
uniprotkb:Q15087
uniprotkb:Q15088
uniprotkb:Q16535
uniprotkb:Q16807
uniprotkb:Q16808
uniprotkb:Q16809
uniprotkb:Q16810
uniprotkb:Q16811
uniprotkb:Q16848
uniprotkb:Q86UG1
uniprotkb:Q8J016
uniprotkb:Q99659
uniprotkb:Q9BTM4
uniprotkb:Q9HAQ8
uniprotkb:Q9NP68
uniprotkb:Q9NPJ2
uniprotkb:Q9NZD0
uniprotkb:Q9UBI2
uniprotkb:Q9UQ61
intact:EBI-28980681
ensembl:ENSP00000269305.4
ensembl:ENSP00000391478.2
ensembl:ENSP00000424104.2
ensembl:ENSP00000426252.2
uniprotkb:Q2XN98
uniprotkb:Q3LRW1
uniprotkb:Q3LRW2
uniprotkb:Q3LRW3
uniprotkb:Q3LRW4
uniprotkb:Q3LRW5
Alternative identifier for interactor Bintact:EBI-80830
uniprotkb:Q9Y5U0
uniprotkb:O00613
uniprotkb:O15416
uniprotkb:Q13354
uniprotkb:O15421
intact:EBI-28976851
uniprotkb:Q56D06
uniprotkb:Q59GM0
ensembl:ENSP00000384018.1
Aliases for Apsi-mi:p53_human(display_long)
uniprotkb:TP53(gene name)
psi-mi:TP53(display_short)
uniprotkb:P53(gene name synonym)
uniprotkb:Tumor suppressor p53(gene name synonym)
uniprotkb:Phosphoprotein p53(gene name synonym)
uniprotkb:Antigen NY-CO-13(gene name synonym)
Aliases for Bpsi-mi:ncor2_human(display_long)
uniprotkb:NCOR2(gene name)
psi-mi:NCOR2(display_short)
uniprotkb:CTG26(gene name synonym)
uniprotkb:Silencing mediator of retinoic acid and thyroid hormone receptor(gene name synonym)
uniprotkb:Thyroid-, retinoic-acid-receptor-associated corepressor(gene name synonym)
uniprotkb:T3 receptor-associating factor(gene name synonym)
uniprotkb:CTG repeat protein 26(gene name synonym)
uniprotkb:SMAP270(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorAdikesavan et al. (2014)
Identifier of the publicationimex:IM-24144
pubmed:24449765
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-10814995
imex:IM-24144-7
Confidence scoreintact-miscore:0.65
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f6c f6d f7b f9a
comment:"\"to define the region of SMRT that interacts with p53, C-terminal and N-terminal fragments of SMRT (SMRT-CT and SMRT-NT, respectively) were tested for their ability to bind to p53. Pulldown studies demonstrated that GST-p53, but not the GST control, was able to interact strongly with SMRT-NT, whereas the interaction between the SMRT-CT deletion mutant and GST-p53 was very weak\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2015/05/04
Update date2024/09/13
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:300-393
Feature(s) for interactor Bbinding-associated region:389-480
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BAutoradiography