| Unique identifier for interactor A | uniprotkb:Q09472 |
| Unique identifier for interactor B | uniprotkb:Q16665 |
| Alternative identifier for interactor A | intact:EBI-447295 ensembl:ENSP00000263253.7 intact:EBI-3908041 uniprotkb:B1AKC2 intact:EBI-28987257 |
| Alternative identifier for interactor B | intact:EBI-447269 uniprotkb:Q53XP6 uniprotkb:Q96PT9 uniprotkb:Q9UPB1 uniprotkb:C0LZJ3 ensembl:ENSP00000338018.4 |
| Aliases for A | psi-mi:ep300_human(display_long) uniprotkb:Histone butyryltransferase p300(gene name synonym) uniprotkb:Histone crotonyltransferase p300(gene name synonym) uniprotkb:Protein propionyltransferase p300(gene name synonym) uniprotkb:EP300(gene name) psi-mi:EP300(display_short) uniprotkb:P300(gene name synonym) uniprotkb:E1A-associated protein p300(gene name synonym) uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym) uniprotkb:Protein lactyltransferas p300(gene name synonym) |
| Aliases for B | psi-mi:hif1a_human(display_long) uniprotkb:ARNT-interacting protein(gene name synonym) uniprotkb:Member of PAS protein 1(gene name synonym) uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym) uniprotkb:HIF1A(gene name) psi-mi:HIF1A(display_short) uniprotkb:MOP1(gene name synonym) uniprotkb:BHLHE78(gene name synonym) uniprotkb:PASD8(gene name synonym) uniprotkb:PAS domain-containing protein 8(gene name synonym) uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Chen et al. (2014) |
| Identifier of the publication | imex:IM-24069 pubmed:24421387 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-10766857 imex:IM-24069-7 |
| Confidence score | intact-miscore:0.96 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f7b f7c comment:"\"To further confirm whether EAF2’s effect is due to the disruption of HIF-1and p300, we performed binding assays. As expected, increased EAF2 levels weakened the binding between HIF-1 and p300 (Fig. 7B). Moreover, the EAF2 III-VI mutant, which could not bind to HIF-1, lost its ability to disrupt the binding between HIF-1 and p300 (Fig. 7C; compare columns 3 and 4, top row). Sub\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293t) taxid:9606(Homo sapiens HEK293T embryonic kidney cell) |
| Parameters of the interaction | - |
| Creation date | 2015/04/20 |
| Update date | 2024/09/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | ha tag:?-? |
| Feature(s) for interactor B | flag tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Anti tag western blot |
| Participant identification method for interactor B | Anti tag western blot |