| Unique identifier for interactor A | uniprotkb:Q13098 |
| Unique identifier for interactor B | uniprotkb:P61201 |
| Alternative identifier for interactor A | intact:EBI-725197 uniprotkb:Q8NA10 uniprotkb:Q9BWL1 ensembl:ENSP00000302873.6 |
| Alternative identifier for interactor B | intact:EBI-1050386 uniprotkb:O88950 uniprotkb:Q15647 uniprotkb:Q6FGP4 uniprotkb:Q9BY54 uniprotkb:Q9R249 uniprotkb:Q9UNI2 uniprotkb:Q9UNQ5 ensembl:ENSP00000373553.5 |
| Aliases for A | psi-mi:csn1_human(display_long) uniprotkb:JAB1-containing signalosome subunit 1(gene name synonym) uniprotkb:G protein pathway suppressor 1(gene name synonym) uniprotkb:Protein MFH(gene name synonym) uniprotkb:GPS1(gene name) psi-mi:GPS1(display_short) uniprotkb:COPS1(gene name synonym) uniprotkb:CSN1(gene name synonym) |
| Aliases for B | psi-mi:csn2_human(display_long) uniprotkb:JAB1-containing signalosome subunit 2(gene name synonym) uniprotkb:Thyroid receptor-interacting protein 15(gene name synonym) uniprotkb:Alien homolog(gene name synonym) uniprotkb:COPS2(gene name) psi-mi:COPS2(display_short) uniprotkb:CSN2(gene name synonym) uniprotkb:TRIP15(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0028"(cosedimentation in solution) |
| First author | Füzesi-Levi et al. (2014) |
| Identifier of the publication | pubmed:24421388 imex:IM-24066 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-10766278 imex:IM-24066-19 |
| Confidence score | intact-miscore:0.81 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f2a comment:"\"We therefore explored whether the subcellular partitioning of the complex changes during the different stages of the cell cycle. To test this hypothesis, we synchronized HeLa cells using a double-thymidine block. Protein extracts were prepared at various time points following their release from the block, and the cell cycle state was evaluated by flow cytometry. The expression level ofCSNsubunits within each cellular compartment was then examined by Western blot analyses. Our analysis indicates that although we could clearly detect the expected oscillation in the levels of the cell cycle regulator, cyclin E, the cellular levels of CSN subunits remained constant throughout the cell cycle (Fig. 4).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hela) taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2015/04/15 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |