| Unique identifier for interactor A | uniprotkb:Q9NRF2 |
| Unique identifier for interactor B | uniprotkb:P52631 |
| Alternative identifier for interactor A | intact:EBI-310491 intact:EBI-28975758 ensembl:ENSP00000321221.7 ensembl:ENSP00000481709.1 ensembl:ENSP00000507475.1 uniprotkb:A8K2R7 uniprotkb:Q96FK3 uniprotkb:Q96SX3 uniprotkb:Q9NRF1 uniprotkb:Q9NRF3 uniprotkb:Q9Y3Y3 uniprotkb:Q9P2P7 |
| Alternative identifier for interactor B | intact:EBI-10764775 ensembl:ENSRNOP00000026760.3 ensembl:ENSRNOP00055045927 ensembl:ENSRNOP00060017357 ensembl:ENSRNOP00065041898 |
| Aliases for A | psi-mi:sh2b1_human(display_long) uniprotkb:SH2B1(gene name) psi-mi:SH2B1(display_short) uniprotkb:KIAA1299(gene name synonym) uniprotkb:SH2B(gene name synonym) uniprotkb:SH2 domain-containing protein 1B(gene name synonym) uniprotkb:Pro-rich, PH and SH2 domain-containing signaling mediator(gene name synonym) |
| Aliases for B | psi-mi:stat3_rat(display_long) uniprotkb:Stat3(gene name) psi-mi:Stat3(display_short) |
| Interaction detection methods | psi-mi:"MI:0813"(proximity ligation assay) |
| First author | Chang et al. (2014) |
| Identifier of the publication | imex:IM-24055 pubmed:24396070 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
| Interaction types | psi-mi:"MI:2364"(proximity) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-10764864 imex:IM-24055-13 |
| Confidence score | intact-miscore:0.47 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f3d comment:"\"To confirm the coimmunoprecipitation results, Duolink in situ PLAs were used to examine the association between SH2B1 and STAT3 in response to FGF1. PC12-SH2B1 cells were left untreated or were treated with FGF1, followed by incubation with anti-GFP (detect GFP-SH2B1) and anti-STAT3 antibodies and then reaction with in situ PLA probes and reagents. The interactions between SH2B1 and STAT3 were detected by fluorescent punctate signal. In response to FGF1 stimulation, levels of SH2B1-STAT3 complexes increased (Fig. 3D).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:10116(rat-pc12) taxid:10116(Rattus norvegicus PC12 cells) |
| Parameters of the interaction | - |
| Creation date | 2015/04/09 |
| Update date | 2015/04/10 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Identification by antibody |
| Participant identification method for interactor B | Identification by antibody |