| Unique identifier for interactor A | uniprotkb:Q9WTN3 |
| Unique identifier for interactor B | uniprotkb:P63166 |
| Alternative identifier for interactor A | intact:EBI-5273743 uniprotkb:Q3U458 uniprotkb:Q3UDJ3 uniprotkb:Q5SRX5 uniprotkb:Q8C733 uniprotkb:Q99JK7 ensembl:ENSMUSP00000020846.2 |
| Alternative identifier for interactor B | intact:EBI-80152 uniprotkb:P55856 uniprotkb:Q3TX92 uniprotkb:Q93068 ensembl:ENSMUSP00000088935.3 |
| Aliases for A | psi-mi:srbp1_mouse(display_long) uniprotkb:Srebf1(gene name) psi-mi:Srebf1(display_short) uniprotkb:Srebp1(gene name synonym) uniprotkb:Sterol regulatory element-binding transcription factor 1(gene name synonym) |
| Aliases for B | psi-mi:sumo1_mouse(display_long) uniprotkb:Sumo1(gene name) psi-mi:Sumo1(display_short) uniprotkb:Smt3c(gene name synonym) uniprotkb:Smt3h3(gene name synonym) uniprotkb:Ubl1(gene name synonym) uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym) uniprotkb:SMT3 homolog 3(gene name synonym) uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0813"(proximity ligation assay) |
| First author | Lee et al. (2014) |
| Identifier of the publication | imex:IM-24052 pubmed:24379443 |
| NCBI Taxonomy identifier for interactor A | taxid:10090(mouse) taxid:10090(Mus musculus) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:2364"(proximity) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-10764247 imex:IM-24052-3 |
| Confidence score | intact-miscore:0.47 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f6d comment:"\"To explore these results at the cellular level, we investigated SREBP1c sumoylation via in situ proximity ligation assay (PLA), which allowed us to monitor protein modifications and, indirectly, physical interactions. As shown in Fig. 6D and E, SREBP1c sumoylation was detected in endogenous and exogenous SREBP1c protein from mouse primary hepatocytes and HeLa cells, respectively. Although PLA-positive signals (shown in red) indicated relatively weak SREBP1c sumoylation in primary hepatocytes, the mean number of PLA-positive red clusters per cell was augmented by forskolin, whereas these signals were decreased by H89 pretreatment (Fig. 6D and data not shown).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:10090(mouse-hepatocyte) taxid:10090(Mouse hepatocyte) |
| Parameters of the interaction | - |
| Creation date | 2015/04/08 |
| Update date | 2024/09/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Identification by antibody |
| Participant identification method for interactor B | Identification by antibody |