Curation Details
Interaction ID: IM-24039-40

Unique identifier for interactor Auniprotkb:Q9Z2X8
Unique identifier for interactor Buniprotkb:Q60795
Alternative identifier for interactor Aintact:EBI-647110
uniprotkb:Q3U243
uniprotkb:Q3U8N7
uniprotkb:Q547S3
uniprotkb:Q6ZQI6
uniprotkb:Q8BQY3
ensembl:ENSMUSP00000062467.5
ensembl:ENSMUSP00000131029.2
ensembl:ENSMUSP00000141807.2
ensembl:ENSMUSP00000141840.2
Alternative identifier for interactor Bintact:EBI-642563
ensembl:ENSMUSP00000099733.5
uniprotkb:Q3UQK0
Aliases for Apsi-mi:keap1_mouse(display_long)
uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)
uniprotkb:Keap1(gene name)
psi-mi:Keap1(display_short)
uniprotkb:Inrf2(gene name synonym)
uniprotkb:Kiaa0132(gene name synonym)
Aliases for Bpsi-mi:nf2l2_mouse(display_long)
uniprotkb:Nuclear factor, erythroid derived 2, like 2(gene name synonym)
uniprotkb:Nfe2l2(gene name)
psi-mi:Nfe2l2(display_short)
uniprotkb:Nrf2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0114"(x-ray crystallography)
First authorFukutomi et al. (2014)
Identifier of the publicationpubmed:24366543
imex:IM-24039
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-10760678
imex:IM-24039-40
Confidence scoreintact-miscore:0.82
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:t2 f6 f7
comment:"\"we crystallized Keap1-DC in complex with a long DLG peptide, DLGex(Met17-Gln51), and analyzed the crystal by X-ray diffraction at a 1.6 Å resolution (Table 2). The asymmetric unit contains two heterodimers of Keap1-DC-DLGex (chains A to B and L to M).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2015/03/30
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:321-609
Feature(s) for interactor Bbinding-associated region:17-51
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant