| Unique identifier for interactor A | uniprotkb:P08253 |
| Unique identifier for interactor B | uniprotkb:Q80W65 |
| Alternative identifier for interactor A | intact:EBI-1033518 uniprotkb:B2R6U1 uniprotkb:Q9UCJ8 uniprotkb:E9PE45 uniprotkb:B4DWH3 ensembl:ENSP00000219070.4 |
| Alternative identifier for interactor B | intact:EBI-10634657 uniprotkb:B1AZI4 uniprotkb:Q3UEH7 uniprotkb:Q8BXW9 uniprotkb:Q8CFT6 ensembl:ENSMUSP00000055757.6 |
| Aliases for A | psi-mi:mmp2_human(display_long) uniprotkb:MMP2(gene name) psi-mi:MMP2(display_short) uniprotkb:CLG4A(gene name synonym) uniprotkb:72 kDa gelatinase(gene name synonym) uniprotkb:Matrix metalloproteinase-2(gene name synonym) uniprotkb:Gelatinase A(gene name synonym) uniprotkb:TBE-1(gene name synonym) |
| Aliases for B | psi-mi:pcsk9_mouse(display_long) uniprotkb:Pcsk9(gene name) psi-mi:Pcsk9(display_short) uniprotkb:Narc1(gene name synonym) uniprotkb:Neural apoptosis-regulated convertase 1(gene name synonym) uniprotkb:Proprotein convertase 9(gene name synonym) uniprotkb:Subtilisin/kexin-like protease PC9(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0415"(enzymatic study) |
| First author | Wang et al. (2015) |
| Identifier of the publication | pubmed:25613181 imex:IM-23861 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:0194"(cleavage reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-10634649 imex:IM-23861-2 |
| Confidence score | intact-miscore:0.44 |
| Complex expansion | - |
| Biological role A | Enzyme |
| Biological role B | Enzyme target |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:sf2 f2b st2 comment:"\"two putative cleavage sites both occurring at Gly;Ile bonds proximal to the C-terminus of PCSK9 (Supplementary Fig. 2)\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2015/02/16 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | protein modification:397-397 protein modification:617-617 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Identification by mass spectrometry |