Curation Details
Interaction ID: IM-23846-6

Unique identifier for interactor Auniprotkb:P62993
Unique identifier for interactor Buniprotkb:P29350
Alternative identifier for interactor Aintact:EBI-401755
ensembl:ENSP00000339007.4
ensembl:ENSP00000376345.1
ensembl:ENSP00000376347.1
ensembl:ENSP00000496913.1
uniprotkb:P29354
uniprotkb:Q14450
uniprotkb:Q63057
uniprotkb:Q63059
Alternative identifier for interactor Bintact:EBI-78260
uniprotkb:A8K306
uniprotkb:G3V0F8
uniprotkb:Q9UK67
ensembl:ENSP00000326010.9
intact:EBI-28977917
uniprotkb:Q969V8
Aliases for Apsi-mi:grb2_human(display_long)
uniprotkb:GRB2(gene name)
psi-mi:GRB2(display_short)
uniprotkb:ASH(gene name synonym)
uniprotkb:Adapter protein GRB2(gene name synonym)
uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)
uniprotkb:Protein Ash(gene name synonym)
Aliases for Bpsi-mi:ptn6_human(display_long)
uniprotkb:PTPN6(gene name)
psi-mi:PTPN6(display_short)
uniprotkb:HCP(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)
uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)
uniprotkb:SH-PTP1(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)
uniprotkb:PTP1C(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorPaster et al. (2015)
Identifier of the publicationpubmed:25535246
imex:IM-23846
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-10636474
imex:IM-23846-6
Confidence scoreintact-miscore:0.65
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1f
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2015/02/17
Update date2015/02/17
negative Boolean valuefalse
Feature(s) for interactor Amyc tag:c-c
mutation disrupting interaction:36-36
Feature(s) for interactor Bha tag:n-n
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot