Curation Details
Interaction ID: IM-23810-33

Unique identifier for interactor Auniprotkb:Q9GZQ8
Unique identifier for interactor Buniprotkb:Q8IZQ1
Alternative identifier for interactor Aintact:EBI-373144
ensembl:ENSP00000268607.5
ensembl:ENSP00000498476.1
intact:EBI-28979688
uniprotkb:Q6NW02
Alternative identifier for interactor Bintact:EBI-1569256
ensembl:ENSP00000295888.4
uniprotkb:Q4W5K5
uniprotkb:Q6P0Q5
uniprotkb:Q8N1T2
uniprotkb:Q8NAV6
uniprotkb:Q96BS7
uniprotkb:Q96D33
uniprotkb:Q96N85
uniprotkb:Q9Y2J7
Aliases for Apsi-mi:mlp3b_human(display_long)
uniprotkb:MAP1LC3B(gene name)
psi-mi:MAP1LC3B(display_short)
uniprotkb:MAP1ALC3(gene name synonym)
uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)
uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)
uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)
uniprotkb:Autophagy-related protein LC3 B(gene name synonym)
uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym)
Aliases for Bpsi-mi:wdfy3_human(display_long)
uniprotkb:Autophagy-linked FYVE protein(gene name synonym)
uniprotkb:WDFY3(gene name)
psi-mi:WDFY3(display_short)
uniprotkb:KIAA0993(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorLystad et al. (2014)
Identifier of the publicationpubmed:24668264
imex:IM-23810
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-10107587
imex:IM-23810-33
Confidence scoreintact-miscore:0.71
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:sf5b
comment:"\"while overexpressed ALFY2285–3526 did not colocalize with wild-type GFP- LC3B, colocalization was observed upon the induction of excess GABARAP (Supplementary Fig S5B) or expression of the GFP-LC3B (Q26K/H27Y/H57D) mutant (Supplementary Fig S5B), indicating that the structural determinants identified as being important for GABARAP-ALFY binding specificity also determine colocalization between these proteins.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2015/02/03
Update date2015/02/06
negative Boolean valuefalse
Feature(s) for interactor Agreen fluorescent protein tag:?-?
mutation increasing interaction:26-26,27-27,57-57
Feature(s) for interactor Bbinding-associated region:2285-3526
mcherry fluorescent protein tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ATag visualisation by fluorescence
Participant identification method for interactor BTag visualisation by fluorescence