Unique identifier for interactor A | uniprotkb:Q96QK1 |
Unique identifier for interactor B | uniprotkb:Q7Z3C6 |
Alternative identifier for interactor A | intact:EBI-1054634 ensembl:ENSP00000299138.7 uniprotkb:Q561W2 uniprotkb:Q9H016 uniprotkb:Q9H096 uniprotkb:Q9H4P3 uniprotkb:Q9H8J0 uniprotkb:Q9NRS7 uniprotkb:Q9NVG2 uniprotkb:Q9NX80 uniprotkb:Q9NZK2 |
Alternative identifier for interactor B | intact:EBI-727146 ensembl:ENSP00000355173.4 ensembl:ENSP00000379983.2 ensembl:ENSP00000386710.1 uniprotkb:Q6P0N7 uniprotkb:Q7Z317 uniprotkb:Q7Z320 uniprotkb:Q8NDK6 uniprotkb:Q8WU65 uniprotkb:Q9BVL5 uniprotkb:Q9H6L1 uniprotkb:Q9HAG7 uniprotkb:Q3ZAQ6 |
Aliases for A | psi-mi:vps35_human(display_long) uniprotkb:Vesicle protein sorting 35(gene name synonym) uniprotkb:Maternal-embryonic 3(gene name synonym) uniprotkb:VPS35(gene name) psi-mi:VPS35(display_short) uniprotkb:MEM3(gene name synonym) uniprotkb:TCCCTA00141(orf name) |
Aliases for B | psi-mi:atg9a_human(display_long) uniprotkb:APG9-like 1(gene name synonym) uniprotkb:ATG9A(gene name) psi-mi:ATG9A(display_short) uniprotkb:APG9L1(gene name synonym) uniprotkb:mATG9(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
First author | Popovic et al. (2014) |
Identifier of the publication | pubmed:24603492 imex:IM-23790 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0403"(colocalization) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-10104110 imex:IM-23790-2 |
Confidence score | intact-miscore:0.46 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Neutral component |
Experimental role B | Neutral component |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:f1a f1c sf1a sf1c comment:"\"In U2OS cells stably expressing mCherry-ATG9, endogenous TBC1D5, retromer subunit VPS35, and mCherry-ATG9 co-localized in steady state as well as during autophagy induced by the mTOR inhibitor KU0063974 (Fig1A). Closer inspection of ATG9-containing vesicles showed that ATG9 does not enter retromer-associated endosomal tubules (Supplementary Fig S1A). Co-localization of TBC1D5 with ATG9 was steadily high in both tested conditions (Fig 1B), while retromer co-localization decreased upon autophagy induction (Fig 1C). Endogenous ATG9, LC3, and TBC1D5 also co-localized in cells (Supplementary Fig S1B).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
NCBI Taxonomy identifier for the host organism | taxid:9606(human-u2os) taxid:9606(Homo sapiens U2OS osteosarcoma cell) |
Parameters of the interaction | - |
Creation date | 2014/10/06 |
Update date | 2015/02/04 |
negative Boolean value | false |
Feature(s) for interactor A | - |
Feature(s) for interactor B | mcherry fluorescent protein tag:?-? |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Immunostaining |
Participant identification method for interactor B | Tag visualisation by fluorescence |