Curation Details
Interaction ID: IM-23790-15

Unique identifier for interactor Auniprotkb:O95782
Unique identifier for interactor Buniprotkb:Q7Z3C6
Alternative identifier for interactor Aintact:EBI-353552
uniprotkb:Q96CI7
uniprotkb:Q96PP6
uniprotkb:Q96PP7
uniprotkb:Q9H070
intact:EBI-28973302
ensembl:ENSP00000351926.4
Alternative identifier for interactor Bintact:EBI-727146
uniprotkb:Q6P0N7
uniprotkb:Q7Z317
uniprotkb:Q7Z320
uniprotkb:Q8NDK6
uniprotkb:Q8WU65
uniprotkb:Q9BVL5
uniprotkb:Q9H6L1
uniprotkb:Q9HAG7
uniprotkb:Q3ZAQ6
ensembl:ENSP00000355173.4
ensembl:ENSP00000379983.2
ensembl:ENSP00000386710.1
Aliases for Apsi-mi:ap2a1_human(display_long)
uniprotkb:AP2A1(gene name)
psi-mi:AP2A1(display_short)
uniprotkb:ADTAA(gene name synonym)
uniprotkb:CLAPA1(gene name synonym)
uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)
uniprotkb:Alpha1-adaptin(gene name synonym)
uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)
uniprotkb:Alpha-adaptin A(gene name synonym)
uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)
uniprotkb:100 kDa coated vesicle protein A(gene name synonym)
uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)
Aliases for Bpsi-mi:atg9a_human(display_long)
uniprotkb:APG9-like 1(gene name synonym)
uniprotkb:ATG9A(gene name)
psi-mi:ATG9A(display_short)
uniprotkb:APG9L1(gene name synonym)
uniprotkb:mATG9(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorPopovic et al. (2014)
Identifier of the publicationpubmed:24603492
imex:IM-23790
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-10105726
imex:IM-23790-15
Confidence scoreintact-miscore:0.43
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:sf6
comment:"\"Moreover, TBC1D5 and ATG9 co-localized with the AP2 complex (Fig 3D, Supplementary Fig S6A). Importantly, co- localization of ATG9 with AP2 was enhanced during autophagy (Fig 3E, Supplementary Fig S6B) and readily disturbed upon the depletion of TBC1D5 (Supplementary Fig S6B).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-u2os)
taxid:9606(Homo sapiens U2OS osteosarcoma cell)
Parameters of the interaction-
Creation date2014/10/06
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BImmunostaining