| Unique identifier for interactor A | uniprotkb:Q92609 |
| Unique identifier for interactor B | uniprotkb:O70405 |
| Alternative identifier for interactor A | intact:EBI-742381 uniprotkb:A6NP25 intact:EBI-28978959 uniprotkb:C9JP52 ensembl:ENSP00000253692.6 ensembl:ENSP00000398127.4 |
| Alternative identifier for interactor B | intact:EBI-8390771 intact:UNK-5365168 uniprotkb:Q6PGB2 |
| Aliases for A | psi-mi:tbcd5_human(display_long) uniprotkb:TBC1D5(gene name) psi-mi:TBC1D5(display_short) uniprotkb:KIAA0210(gene name synonym) |
| Aliases for B | psi-mi:ulk1_mouse(display_long) uniprotkb:Ulk1(gene name) psi-mi:Ulk1(display_short) uniprotkb:Unc-51-like kinase 1(gene name synonym) uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Popovic et al. (2014) |
| Identifier of the publication | pubmed:24603492 imex:IM-23790 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-10104351 imex:IM-23790-10 |
| Confidence score | intact-miscore:0.27 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:sf3 comment:"\"In U2OS cells stably expressing mCherry-ATG9, endogenous TBC1D5, retromer subunit VPS35, and mCherry-ATG9 co-localized in steady state as well as during autophagy induced by the mTOR inhibitor KU0063974 (Fig1A). Closer inspection of ATG9-containing vesicles showed that ATG9 does not enter retromer-associated endosomal tubules (Supplementary Fig S1A). Co-localization of TBC1D5 with ATG9 was steadily high in both tested conditions (Fig 1B), while retromer co-localization decreased upon autophagy induction (Fig 1C). Endogenous ATG9, LC3, and TBC1D5 also co-localized in cells (Supplementary Fig S1B).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-u2os) taxid:9606(Homo sapiens U2OS osteosarcoma cell) |
| Parameters of the interaction | - |
| Creation date | 2014/10/06 |
| Update date | 2024/09/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | ha tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Immunostaining |
| Participant identification method for interactor B | Anti tag immunostaining |