| Unique identifier for interactor A | ensembl:ENSG00000136997 |
| Unique identifier for interactor B | uniprotkb:O15379 |
| Alternative identifier for interactor A | intact:EBI-1265559 |
| Alternative identifier for interactor B | intact:EBI-607682 uniprotkb:O43268 uniprotkb:Q9UEI5 uniprotkb:Q9UEV0 uniprotkb:D3DQE1 ensembl:ENSP00000302967.3 |
| Aliases for A | psi-mi:myc_human_gene(display_short) psi-mi:ENSG00000136997(display_long) |
| Aliases for B | psi-mi:hdac3_human(display_long) uniprotkb:HDAC3(gene name) psi-mi:HDAC3(display_short) uniprotkb:Protein deacetylase HDAC3(gene name synonym) uniprotkb:Protein deacylase HDAC3(gene name synonym) uniprotkb:RPD3-2(gene name synonym) uniprotkb:SMAP45(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0402"(chromatin immunoprecipitation assay) |
| First author | Qinyu et al. (2013) |
| Identifier of the publication | mint:MINT-8429205 mint:d-13-00389r2 pubmed:23714368 imex:IM-23656 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-10050363 imex:IM-23656-5 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Gene |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:Fig. 5f, 5g agonist:anti-FOXO6 siRNA caution:"\"According to the figure legend (5g), cells are transfected with siRNA targeting HNF4; however, both the text and figure clearly indicate that cells are transfected with siRNA targeting FOXO6.\"" comment:Overexpression of FOXO6 decreased binding of HDAC3 to c-Myc promoter DNA; however, the origin of the FOXO6 expression construct could not be determined. causality statement:A8MYZ6 decreases binding of O15379 to ENSG00000136997 curation depth:imex curation full coverage:Only protein-protein interactions dataset:IBD - Inflammatory bowel disease dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-snu-16) taxid:9606(Homo sapiens SNU-16 gastric adenocarcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2013/05/15 |
| Update date | 2024/09/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:?-? |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Quantitative pcr |
| Participant identification method for interactor B | Quantitative pcr |