| Unique identifier for interactor A | uniprotkb:P41235 |
| Unique identifier for interactor B | ensembl:ENSG00000136997 |
| Alternative identifier for interactor A | intact:EBI-1049011 uniprotkb:Q92654 uniprotkb:Q92655 uniprotkb:Q99864 uniprotkb:Q9NQH0 uniprotkb:O00659 uniprotkb:O00723 uniprotkb:Q14540 uniprotkb:Q5QPB8 uniprotkb:Q6B4V5 uniprotkb:Q6B4V6 uniprotkb:Q6B4V7 uniprotkb:Q92653 uniprotkb:A5JW41 uniprotkb:B2RPP8 ensembl:ENSP00000312987.3 |
| Alternative identifier for interactor B | intact:EBI-1265559 |
| Aliases for A | psi-mi:hnf4a_human(display_long) uniprotkb:Transcription factor HNF-4(gene name synonym) uniprotkb:Nuclear receptor subfamily 2 group A member 1(gene name synonym) uniprotkb:Transcription factor 14(gene name synonym) uniprotkb:HNF4A(gene name) psi-mi:HNF4A(display_short) uniprotkb:HNF4(gene name synonym) uniprotkb:NR2A1(gene name synonym) uniprotkb:TCF14(gene name synonym) |
| Aliases for B | psi-mi:myc_human_gene(display_short) psi-mi:ENSG00000136997(display_long) |
| Interaction detection methods | psi-mi:"MI:0402"(chromatin immunoprecipitation assay) |
| First author | Qinyu et al. (2013) |
| Identifier of the publication | mint:MINT-8429205 mint:d-13-00389r2 pubmed:23714368 imex:IM-23656 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-10050354 imex:IM-23656-4 |
| Confidence score | intact-miscore:0.35 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Gene |
| Annotations for the interaction | figure legend:Fig. 5d, 5e, Suppl. Fig. S2a, S3 antagonist:anti-FOXO6 siRNA comment:Overexpression of FOXO6 increased binding of HNF4 to c-Myc promoter DNA; however, the origin of the FOXO6 expression construct could not be determined. caution:"\"According to the figure legend (5e), cells are transfected with siRNA targeting HNF4; however, both the text and figure clearly indicate that cells are transfected with siRNA targeting FOXO6.\"" causality statement:P41235 increases expression at RNA level of ENSG00000136997 causality statement:P41235 increases expression at protein level of ENSG00000136997 causality statement:A8MYZ6 increases binding of P41235 to ENSG00000136997 curation depth:imex curation full coverage:Only protein-protein interactions dataset:IBD - Inflammatory bowel disease dataset:Ulcerative colitis - Interactions of proteins identified as having a link to ulcerative colitis |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-snu-16) taxid:9606(Homo sapiens SNU-16 gastric adenocarcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2013/05/15 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | binding-associated region:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Quantitative pcr |
| Participant identification method for interactor B | Quantitative pcr |