Curation Details
Interaction ID: IM-23253-3

Unique identifier for interactor Aensembl:ENSG00000187555
Unique identifier for interactor Buniprotkb:Q13547
Alternative identifier for interactor Aintact:EBI-9875449
Alternative identifier for interactor Bintact:EBI-301834
ensembl:ENSP00000362649.3
uniprotkb:Q92534
Aliases for Apsi-mi:ubp7_human_gene(display_short)
psi-mi:ENSG00000187555(display_long)
Aliases for Bpsi-mi:hdac1_human(display_long)
uniprotkb:HDAC1(gene name)
psi-mi:HDAC1(display_short)
uniprotkb:RPD3L1(gene name synonym)
uniprotkb:Protein deacetylase HDAC1(gene name synonym)
uniprotkb:Protein decrotonylase HDAC1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0402"(chromatin immunoprecipitation assay)
First authorYang et al. (2012)
Identifier of the publicationpubmed:22750444
mint:MINT-8383056
imex:IM-23253
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9875465
imex:IM-23253-3
Confidence scoreintact-miscore:0.35
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AGene
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 3h, 3i
agonist:"\"Interleukin-6 (IL-6)\""
causality statement:Q13547 decreases expression at RNA level of ENSG00000187555
causality statement:Q13547 decreases expression at protein level of ENSG00000187555
causality statement:P40763 increases binding of Q13547 to ENSG00000187555
dataset:IBD - Inflammatory bowel disease
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-sw480)
taxid:9606(Homo sapiens SW480 adenocarcinoma cell)
Parameters of the interaction-
Creation date2012/06/18
Update date2014/10/30
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APrimer specific pcr
Participant identification method for interactor BPrimer specific pcr