Curation Details
Interaction ID: IM-23253-2

Unique identifier for interactor Auniprotkb:P40763
Unique identifier for interactor Bensembl:ENSG00000187555
Alternative identifier for interactor Aintact:EBI-518675
uniprotkb:K7ENL3
ensembl:ENSP00000264657.4
ensembl:ENSP00000467985.1
ensembl:ENSP00000503102.1
ensembl:ENSP00000503181.1
ensembl:ENSP00000504184.1
uniprotkb:O14916
uniprotkb:Q9BW54
uniprotkb:A8K7B8
Alternative identifier for interactor Bintact:EBI-9875449
Aliases for Apsi-mi:stat3_human(display_long)
uniprotkb:Acute-phase response factor(gene name synonym)
uniprotkb:STAT3(gene name)
psi-mi:STAT3(display_short)
uniprotkb:APRF(gene name synonym)
Aliases for Bpsi-mi:ubp7_human_gene(display_short)
psi-mi:ENSG00000187555(display_long)
Interaction detection methodspsi-mi:"MI:0402"(chromatin immunoprecipitation assay)
First authorYang et al. (2012)
Identifier of the publicationpubmed:22750444
mint:MINT-8383056
imex:IM-23253
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9875459
imex:IM-23253-2
Confidence scoreintact-miscore:0.35
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BGene
Annotations for the interactionfigure legend:Fig. 3b
agonist:"\"Interleukin-6 (IL-6)\""
causality statement:P40763 decreases expression at RNA level of ENSG00000187555
causality statement:P40763 decreases expression at protein level of ENSG00000187555
dataset:IBD - Inflammatory bowel disease
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-sw480)
taxid:9606(Homo sapiens SW480 adenocarcinoma cell)
Parameters of the interaction-
Creation date2012/06/18
Update date2014/10/30
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APrimer specific pcr
Participant identification method for interactor BPrimer specific pcr