Curation Details
Interaction ID: IM-23179-1

Unique identifier for interactor Auniprotkb:Q14254
Unique identifier for interactor Buniprotkb:Q6FHG5
Alternative identifier for interactor Aintact:EBI-348613
ensembl:ENSP00000378368.3
Alternative identifier for interactor Bintact:EBI-9776333
uniprotkb:A6NM47
Aliases for Apsi-mi:flot2_human(display_long)
uniprotkb:FLOT2(gene name)
psi-mi:FLOT2(display_short)
uniprotkb:ESA1(gene name synonym)
uniprotkb:M17S1(gene name synonym)
uniprotkb:Epidermal surface antigen(gene name synonym)
uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym)
Aliases for Bpsi-mi:q6fhg5_human(display_long)
uniprotkb:SNCG(gene name)
psi-mi:SNCG(display_short)
uniprotkb:hCG_23263(orf name)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorLiu et al. (2014)
Identifier of the publicationimex:IM-23179
pubmed:25229320
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9776273
imex:IM-23179-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3b
comment:The association between SNCG and Flotillin-2 in HT-29 and T47D cells was investigated by reciprocal co-immunoprecipitation experiment using the soluble fraction of Cp, which is enriched in plasma membrane and intracellular compartments fractions. As shown in Fig. 3B, interaction between endogenous SNCG and Flotillin-2 was revealed. These results showed that SNCG was associated with membrane vesicles, suggestive of a vesicle-based exporting mechanism of SNCG secretion
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-ht_29)
taxid:9606(Homo sapiens HT-29 colorectal adenocarcinoma cell)
Parameters of the interaction-
Creation date2014/09/12
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot