| Unique identifier for interactor A | uniprotkb:Q14116 |
| Unique identifier for interactor B | uniprotkb:Q13478 |
| Alternative identifier for interactor A | intact:EBI-3910835 uniprotkb:Q6FGY3 uniprotkb:O75599 uniprotkb:Q6WWJ7 intact:EBI-11016725 ensembl:ENSP00000280357.7 ensembl:ENSP00000434161.1 |
| Alternative identifier for interactor B | intact:EBI-9817499 ensembl:ENSP00000233957.1 ensembl:ENSP00000386663.1 ensembl:ENSP00000387211.1 uniprotkb:B2R9Y5 uniprotkb:Q52LC9 |
| Aliases for A | psi-mi:il18_human(display_long) uniprotkb:IL18(gene name) psi-mi:IL18(display_short) uniprotkb:IGIF(gene name synonym) uniprotkb:IL1F4(gene name synonym) uniprotkb:Iboctadekin(gene name synonym) uniprotkb:Interferon gamma-inducing factor(gene name synonym) uniprotkb:Interleukin-1 gamma(gene name synonym) |
| Aliases for B | psi-mi:il18r_human(display_long) uniprotkb:Interleukin-18 receptor alpha(gene name synonym) uniprotkb:IL18R1(gene name) psi-mi:IL18R1(display_short) uniprotkb:IL1RRP(gene name synonym) uniprotkb:CD218 antigen-like family member A(gene name synonym) uniprotkb:CDw218a(gene name synonym) uniprotkb:IL1 receptor-related protein(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0114"(x-ray crystallography) |
| First author | Wei et al. (2014) |
| Identifier of the publication | imex:IM-23178 pubmed:25261253 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9817497 imex:IM-23178-1 |
| Confidence score | intact-miscore:0.56 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:t1 f1 f3 f4 sf2 comment:"\"The final model in the asymmetric unit contains two IL-18-IL-18Rα complexes (Figure S2A), with residues Tyr1-Asn155 in IL-18 and residues Ser21-Cys43, Thr51-Arg71, Arg75-Leu161, Pro169-GLu253, and Asn260-Asp318 in IL-18Rα.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/09/16 |
| Update date | 2024/09/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:37-193 |
| Feature(s) for interactor B | binding-associated region:19-329 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |