Curation Details
Interaction ID: IM-23174-1

Unique identifier for interactor Auniprotkb:Q9UHW5
Unique identifier for interactor Buniprotkb:Q9HCN4
Alternative identifier for interactor Aintact:EBI-395491
uniprotkb:Q53FS3
uniprotkb:Q6UVZ6
uniprotkb:Q7Z3D3
uniprotkb:Q8NEI2
uniprotkb:Q96HK9
uniprotkb:B2RC54
uniprotkb:D4YWV1
uniprotkb:F5H759
ensembl:ENSP00000228827.3
Alternative identifier for interactor Bintact:EBI-745137
uniprotkb:O76004
uniprotkb:B4DQJ5
uniprotkb:B4DXU4
uniprotkb:B4DQM4
uniprotkb:B5MBZ5
ensembl:ENSP00000476446.1
Aliases for Apsi-mi:gpn3_human(display_long)
uniprotkb:ATPBD1C(gene name synonym)
uniprotkb:ATP-binding domain 1 family member C(gene name synonym)
uniprotkb:GPN3(gene name)
psi-mi:GPN3(display_short)
uniprotkb:AD-009(orf name)
uniprotkb:UNQ1876/PRO4319(orf name)
Aliases for Bpsi-mi:gpn1_human(display_long)
uniprotkb:XAB1(gene name synonym)
uniprotkb:XPA-binding protein 1(gene name synonym)
uniprotkb:MBD2-interacting protein(gene name synonym)
uniprotkb:GPN1(gene name)
psi-mi:GPN1(display_short)
uniprotkb:MBDIN(gene name synonym)
uniprotkb:HUSSY-23(orf name)
uniprotkb:RNAPII-associated protein 4(gene name synonym)
uniprotkb:RPAP4(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorMéndez-Hernández et al. (2014)
Identifier of the publicationimex:IM-23174
pubmed:25241168
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9694923
imex:IM-23174-1
Confidence scoreintact-miscore:0.60
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f4a
comment:"\"Gpn3-EYFP coexpressed with Gpn1-Flag displayed a cytoplasmic localization for the 24h that lasted this experiment, in contrast with the nuclear localization of Gpn3-EYFP when expressed alone (Fig 1A), which suggests that Gpn3-EYFP remained associated with Gpn1-Flag at all times (see Fig 4). More importantly, these results indicate that the mobilization of Gpn3-EYFP and Gpn1-Flag into the cell nucleus observed in the presence of LMB very likely occurs as a Gpn3-EYFP/Gpn1-Flag single protein complex. At the single cell level the nuclear accumulation of Gpn3- EYFP in the presence of LMB was always associated with nuclear Gpn1-Flag (Fig. 3A), supporting the proposal that the mobilization of Gpn3-EYFP and Gpn1-Flag occurs as a single complex.\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2014/08/28
Update date2024/11/30
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?
Feature(s) for interactor Byellow fluorescent protein tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot