Curation Details
Interaction ID: IM-23172-1

Unique identifier for interactor Auniprotkb:O15455
Unique identifier for interactor Buniprotkb:O15455
Alternative identifier for interactor Aintact:EBI-6116630
intact:EBI-6289595
uniprotkb:B2RAI7
uniprotkb:E6Y0F0
uniprotkb:E6Y0F1
uniprotkb:Q4VAL2
uniprotkb:Q504W0
uniprotkb:B7Z7K0
uniprotkb:E9PGH4
ensembl:ENSP00000296795.3
Alternative identifier for interactor Bintact:EBI-6116630
intact:EBI-6289595
uniprotkb:B2RAI7
uniprotkb:E6Y0F0
uniprotkb:E6Y0F1
uniprotkb:Q4VAL2
uniprotkb:Q504W0
uniprotkb:B7Z7K0
uniprotkb:E9PGH4
ensembl:ENSP00000296795.3
Aliases for Apsi-mi:tlr3_human(display_long)
uniprotkb:TLR3(gene name)
psi-mi:TLR3(display_short)
Aliases for Bpsi-mi:tlr3_human(display_long)
uniprotkb:TLR3(gene name)
psi-mi:TLR3(display_short)
Interaction detection methodspsi-mi:"MI:0077"(nuclear magnetic resonance)
First authorMineev et al. (2014)
Identifier of the publicationimex:IM-23172
pubmed:25217833
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9694879
imex:IM-23172-1
Confidence scoreintact-miscore:0.74
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1 f2 sfs
comment:we can conclude that TLR3-TM forms dimers and trimers of moderate stability in DPC micelles
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/08/28
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:698-730
Feature(s) for interactor Bbinding-associated region:698-730
Stoichiometry for interactor A2
Stoichiometry for interactor B0
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant