Unique identifier for interactor A | uniprotkb:P20963 |
Unique identifier for interactor B | uniprotkb:P29066 |
Alternative identifier for interactor A | intact:EBI-1165705 uniprotkb:Q5VX13 uniprotkb:Q8TAX4 uniprotkb:B1AK49 ensembl:ENSP00000354782.5 |
Alternative identifier for interactor B | intact:EBI-4303019 |
Aliases for A | psi-mi:cd3z_human(display_long) uniprotkb:T-cell receptor T3 zeta chain(gene name synonym) uniprotkb:CD247(gene name) psi-mi:CD247(display_short) uniprotkb:CD3Z(gene name synonym) uniprotkb:T3Z(gene name synonym) uniprotkb:TCRZ(gene name synonym) |
Aliases for B | psi-mi:arrb1_rat(display_long) uniprotkb:Arrb1(gene name) psi-mi:Arrb1(display_short) uniprotkb:Arrestin beta-1(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
First author | Fernández-Arenas et al. (2014) |
Identifier of the publication | pubmed:24502978 imex:IM-23088 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
Interaction types | psi-mi:"MI:0403"(colocalization) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-9515155 imex:IM-23088-17 |
Confidence score | intact-miscore:0.27 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Neutral component |
Experimental role B | Neutral component |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:f7d comment:"\"We assessed the role of b-Arr1 in mediating CXCR4 translocation to the IS by analyzing Jurkat cells stimulated with superantigen- loaded APCs. In the presence of WT b-Arr1, CXCR4 localized with the TCR at the IS (Fig 7D), whereas expression of b-Arr1 (319- 418) induced the accumulation of both CXCR4 and the TCR in intracellular vesicles, preventing the accumulation of CXCR4 at the IS (Fig 7D).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
NCBI Taxonomy identifier for the host organism | taxid:9606(human-jurkat) taxid:9606(Homo sapiens Jurkat T-cell leukemia cell) |
Parameters of the interaction | - |
Creation date | 2014/04/28 |
Update date | 2024/11/30 |
negative Boolean value | false |
Feature(s) for interactor A | mcherry fluorescent protein tag:?-? |
Feature(s) for interactor B | flag tag:?-? binding-associated region:319-418 |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Tag visualisation by fluorescence |
Participant identification method for interactor B | Anti tag immunostaining |