| Unique identifier for interactor A | uniprotkb:O75943 |
| Unique identifier for interactor B | uniprotkb:O60934 |
| Alternative identifier for interactor A | intact:EBI-968231 uniprotkb:O75714 uniprotkb:Q7Z3S4 uniprotkb:Q9UNK7 uniprotkb:Q9UNR7 uniprotkb:Q9UNR8 uniprotkb:Q9UPF5 uniprotkb:A8K8X2 uniprotkb:D3DWA5 ensembl:ENSP00000370151.3 ensembl:ENSP00000426191.1 ensembl:ENSP00000477962.1 ensembl:ENSP00000477996.1 ensembl:ENSP00000478167.1 ensembl:ENSP00000479160.1 ensembl:ENSP00000482371.1 ensembl:ENSP00000484854.1 |
| Alternative identifier for interactor B | intact:EBI-494844 uniprotkb:O60672 uniprotkb:Q32NF7 uniprotkb:Q53FM6 uniprotkb:Q63HR6 uniprotkb:Q7LDM2 uniprotkb:B2R626 uniprotkb:B2RNC5 ensembl:ENSP00000265433.4 ensembl:ENSP00000513229.1 ensembl:ENSP00000513245.1 |
| Aliases for A | psi-mi:rad17_human(display_long) uniprotkb:R24L(gene name synonym) uniprotkb:RAD17(gene name) psi-mi:RAD17(display_short) uniprotkb:RF-C/activator 1 homolog(gene name synonym) |
| Aliases for B | psi-mi:nbn_human(display_long) uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym) uniprotkb:Cell cycle regulatory protein p95(gene name synonym) uniprotkb:NBN(gene name) psi-mi:NBN(display_short) uniprotkb:NBS1(gene name synonym) uniprotkb:NBS(gene name synonym) uniprotkb:P95(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Wang et al. (2014) |
| Identifier of the publication | imex:IM-23082 pubmed:24534091 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9550529 imex:IM-23082-7 |
| Confidence score | intact-miscore:0.63 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f7a comment:o test this, we synthe- sized biotinylated phospho-T622 Rad17 peptide and control unphos- phorylated peptide with the identical sequence. As shown in Fig 7A, a phospho-T622 Rad17 peptide is able to pull down the FHA domain of NBS1, but not the C-terminal region, with a higher efficiency than the non-phospho-T622 Rad17 peptide, indicating that Thr622 phos- phorylation is directly involved in Rad17-NBS1 interaction. I curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/06/16 |
| Update date | 2024/11/30 |
| negative Boolean value | false |
| Feature(s) for interactor A | phosphorylated residue:633-633 binding-associated region:627-638 |
| Feature(s) for interactor B | glutathione s tranferase tag:?-? binding-associated region:24-100 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Peptide synthesis |
| Participant identification method for interactor B | Molecular weight estimation by coomasie staining |