| Unique identifier for interactor A | uniprotkb:Q9BPX6 |
| Unique identifier for interactor B | uniprotkb:Q9BPX6 |
| Alternative identifier for interactor A | intact:EBI-2371996 uniprotkb:O75785 uniprotkb:Q9H9N6 uniprotkb:Q9UFX0 uniprotkb:A8MV96 uniprotkb:B3KN20 uniprotkb:B4DJH9 uniprotkb:B4DPI1 uniprotkb:B5MBY3 uniprotkb:D3YTJ3 uniprotkb:A0A0U1RRK1 ensembl:ENSP00000354415.5 |
| Alternative identifier for interactor B | intact:EBI-2371996 uniprotkb:O75785 uniprotkb:Q9H9N6 uniprotkb:Q9UFX0 uniprotkb:A8MV96 uniprotkb:B3KN20 uniprotkb:B4DJH9 uniprotkb:B4DPI1 uniprotkb:B5MBY3 uniprotkb:D3YTJ3 uniprotkb:A0A0U1RRK1 ensembl:ENSP00000354415.5 |
| Aliases for A | psi-mi:micu1_human(display_long) uniprotkb:MICU1(gene name) psi-mi:MICU1(display_short) uniprotkb:Calcium-binding atopy-related autoantigen 1(gene name synonym) uniprotkb:CBARA1(gene name synonym) uniprotkb:CALC(gene name synonym) uniprotkb:Atopy-related autoantigen CALC(gene name synonym) |
| Aliases for B | psi-mi:micu1_human(display_long) uniprotkb:MICU1(gene name) psi-mi:MICU1(display_short) uniprotkb:Calcium-binding atopy-related autoantigen 1(gene name synonym) uniprotkb:CBARA1(gene name synonym) uniprotkb:CALC(gene name synonym) uniprotkb:Atopy-related autoantigen CALC(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0114"(x-ray crystallography) |
| First author | Wang et al. (2014) |
| Identifier of the publication | imex:IM-23081 pubmed:24514027 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9550977 imex:IM-23081-5 |
| Confidence score | intact-miscore:0.56 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f3 t1 comment:"\"Ca2+ binding to MICU1 induced large conformational changes in the monomer, which led to a completely different dimer formation. The interface of the Ca2+-bound MICU1-xtal-deltaC dimer was composed of the CH4 helix from both monomers as well as the CH4-CH5 loop from one monomer with the NH3 helix from the reciprocal monomer. The buried surface area of the Ca2+-bound MICU1-xtal-deltaC dimer was approximately 434 A2 (Fig 3B). The overall dimers of the Ca2+-free and the Ca2+-bound MICU1 structures could not be superposed. After the superposition of each monomer from the two dimers, the additional superposition of the second monomer from the two dimers required an approximately 74° rotation (Fig 3C).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/06/17 |
| Update date | 2024/11/28 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:97-444 |
| Feature(s) for interactor B | binding-associated region:97-444 |
| Stoichiometry for interactor A | 2 |
| Stoichiometry for interactor B | 0 |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |