Curation Details
Interaction ID: IM-23072-7

Unique identifier for interactor Auniprotkb:Q9H0H5
Unique identifier for interactor Buniprotkb:Q9H8V3
Alternative identifier for interactor Aintact:EBI-717233
intact:EBI-25411891
ensembl:ENSP00000309871.5
ensembl:ENSP00000404190.2
ensembl:ENSP00000404808.2
ensembl:ENSP00000449370.1
ensembl:ENSP00000449374.1
uniprotkb:Q6PJ26
uniprotkb:Q9NWN2
uniprotkb:Q9P250
uniprotkb:Q9P2W2
Alternative identifier for interactor Bintact:EBI-1054039
uniprotkb:Q9NSV8
uniprotkb:Q9NVW9
ensembl:ENSP00000376457.3
uniprotkb:Q0MT80
uniprotkb:Q6U836
uniprotkb:Q2M269
Aliases for Apsi-mi:rgap1_human(display_long)
uniprotkb:Male germ cell RacGap(gene name synonym)
uniprotkb:RACGAP1(gene name)
psi-mi:RACGAP1(display_short)
uniprotkb:KIAA1478(gene name synonym)
uniprotkb:MGCRACGAP(gene name synonym)
uniprotkb:Protein CYK4 homolog(gene name synonym)
Aliases for Bpsi-mi:ect2_human(display_long)
uniprotkb:Epithelial cell-transforming sequence 2 oncogene(gene name synonym)
uniprotkb:ECT2(gene name)
psi-mi:ECT2(display_short)
Interaction detection methodspsi-mi:"MI:0065"(isothermal titration calorimetry)
First authorZou et al. (2014)
Identifier of the publicationimex:IM-23072
pubmed:25068414
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9663315
imex:IM-23072-7
Confidence scoreintact-miscore:0.88
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3c f4a f4b sf6
comment:"\"After two long peptides were tested, we found that peptide pS157long exhibits no binding to ECT2 (22-326) and peptide pS157/pS164 have similar binding ability as peptide pS164 ((Kd =43.1±13.6 μM) (Fig S6), which suggests that pS157 can not interact with ECT2 even if W167 is accompanied.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkd:42.0x10^-6(molar)
Creation date2014/07/16
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:157-171
phosphorylated residue:164-164
Feature(s) for interactor Bbinding-associated region:22-326
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant