Unique identifier for interactor A | uniprotkb:Q8N490 |
Unique identifier for interactor B | uniprotkb:P27361 |
Alternative identifier for interactor A | intact:EBI-746368 uniprotkb:Q96A48 uniprotkb:Q9BU26 uniprotkb:Q9NSX4 uniprotkb:Q9ULN6 uniprotkb:Q9Y4T1 uniprotkb:A8K1F2 ensembl:ENSP00000273077.4 |
Alternative identifier for interactor B | intact:EBI-73995 uniprotkb:B0LPG3 uniprotkb:A8CZ58 uniprotkb:Q8NHX1 ensembl:ENSP00000263025.4 |
Aliases for A | psi-mi:pnkd_human(display_long) uniprotkb:Paroxysmal nonkinesiogenic dyskinesia protein(gene name synonym) uniprotkb:Myofibrillogenesis regulator 1(gene name synonym) uniprotkb:Trans-activated by hepatitis C virus core protein 2(gene name synonym) uniprotkb:PNKD(gene name) psi-mi:PNKD(display_short) uniprotkb:KIAA1184(gene name synonym) uniprotkb:MR1(gene name synonym) uniprotkb:TAHCCP2(gene name synonym) uniprotkb:FKSG19(orf name) uniprotkb:UNQ2491/PRO5778(orf name) |
Aliases for B | psi-mi:mk03_human(display_long) uniprotkb:ERT2(gene name synonym) uniprotkb:MAP kinase isoform p44(gene name synonym) uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym) uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym) uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym) uniprotkb:p44-ERK1(gene name synonym) uniprotkb:MAPK3(gene name) psi-mi:MAPK3(display_short) uniprotkb:ERK1(gene name synonym) uniprotkb:PRKM3(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
First author | Gong et al. (2014) |
Identifier of the publication | imex:IM-23071 pubmed:25066297 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-9663061 imex:IM-23071-4 |
Confidence score | intact-miscore:0.56 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Bait |
Experimental role B | Prey |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:f6c comment:"\"ERK1 has been detected as endougenously expressed in green monkey cells (COS-7); since its accession number needs to be updated we have adopted the human isoform of the protein, because the antibody also recognizes the human isoform.\"" comment:"\"Co-IP experiments indicated that MR-1 wt and MR-1/57A can interact with ERK1 and MEK1/2, while MR-1/S46A loss the bind with these proteins (Fig. 6C).\"" curation depth:imex curation full coverage:Only protein-protein interactions |
NCBI Taxonomy identifier for the host organism | taxid:9534(chlae-cos_7) taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) |
Parameters of the interaction | - |
Creation date | 2014/07/16 |
Update date | 2024/09/12 |
negative Boolean value | false |
Feature(s) for interactor A | myc tag:?-? mutation disrupting interaction:46-46 |
Feature(s) for interactor B | - |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Western blot |
Participant identification method for interactor B | Western blot |