| Unique identifier for interactor A | uniprotkb:P35555 |
| Unique identifier for interactor B | uniprotkb:P35556 |
| Alternative identifier for interactor A | intact:EBI-2505934 uniprotkb:B2RUU0 uniprotkb:Q15972 uniprotkb:Q75N87 uniprotkb:D2JYH6 ensembl:ENSP00000325527.5 |
| Alternative identifier for interactor B | intact:EBI-6164392 ensembl:ENSP00000262464.4 uniprotkb:B4DU01 uniprotkb:Q59ES6 |
| Aliases for A | psi-mi:fbn1_human(display_long) uniprotkb:FBN1(gene name) psi-mi:FBN1(display_short) uniprotkb:FBN(gene name synonym) |
| Aliases for B | psi-mi:fbn2_human(display_long) uniprotkb:FBN2(gene name) psi-mi:FBN2(display_short) |
| Interaction detection methods | psi-mi:"MI:0892"(solid phase assay) |
| First author | Sabatier et al. (2014) |
| Identifier of the publication | pubmed:25034023 imex:IM-23067 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9636771 imex:IM-23067-1 |
| Confidence score | intact-miscore:0.44 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f3a comment:"\"To investigate whether heparin functionally interferes with the fibrillin N-to-C-terminal interactions, we tested its capacity to inhibit fibrillin homo- and heterotypic interactions (Fig. 3A). Heparin efficiently inhibited both, homotypic and heterotypic interactions of rFBN1-C and rFBN2-C with rFBN1-N and rFBN2-N, suggesting that heparin/heparan sulfate plays aregulatory role at the fibrillin self-assembly stage.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/07/03 |
| Update date | 2024/09/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:1-1361 |
| Feature(s) for interactor B | binding-associated region:1531-2771 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Identification by antibody |