Curation Details
Interaction ID: IM-23062-5

Unique identifier for interactor Auniprotkb:P15559
Unique identifier for interactor Buniprotkb:P15559
Alternative identifier for interactor Aintact:EBI-3989435
uniprotkb:B2R5Y9
uniprotkb:Q86UK1
uniprotkb:B7ZAD1
uniprotkb:B4DNM7
ensembl:ENSP00000319788.5
Alternative identifier for interactor Bintact:EBI-3989435
uniprotkb:B2R5Y9
uniprotkb:Q86UK1
uniprotkb:B7ZAD1
uniprotkb:B4DNM7
ensembl:ENSP00000319788.5
Aliases for Apsi-mi:nqo1_human(display_long)
uniprotkb:NQO1(gene name)
psi-mi:NQO1(display_short)
uniprotkb:DIA4(gene name synonym)
uniprotkb:NMOR1(gene name synonym)
uniprotkb:Azoreductase(gene name synonym)
uniprotkb:DT-diaphorase(gene name synonym)
uniprotkb:Menadione reductase(gene name synonym)
uniprotkb:"NAD(P)H:quinone oxidoreductase 1"(gene name synonym)
uniprotkb:Phylloquinone reductase(gene name synonym)
uniprotkb:Quinone reductase 1(gene name synonym)
Aliases for Bpsi-mi:nqo1_human(display_long)
uniprotkb:NQO1(gene name)
psi-mi:NQO1(display_short)
uniprotkb:DIA4(gene name synonym)
uniprotkb:NMOR1(gene name synonym)
uniprotkb:Azoreductase(gene name synonym)
uniprotkb:DT-diaphorase(gene name synonym)
uniprotkb:Menadione reductase(gene name synonym)
uniprotkb:"NAD(P)H:quinone oxidoreductase 1"(gene name synonym)
uniprotkb:Phylloquinone reductase(gene name synonym)
uniprotkb:Quinone reductase 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0071"(molecular sieving)
First authorLienhart et al. (2014)
Identifier of the publicationpubmed:25143260
imex:IM-23062
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9685585
imex:IM-23062-5
Confidence scoreintact-miscore:0.62
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:sf4
comment:"\"Analytical size exclusion chromatograms of purified NQO1 (continuous line) and NQO1 P187S (Dashed line) obtained using a using a Superdex 200 (10/300) analytical column. The calculated molecular mass of NQO1 (61.3 kDa) and NQO1 P187S (78.33 kDa) indicate that both the proteins exist in dimeric forms. The lower elution volume observed for NQO1 P187S indicates that deviation from the globular structure adopted by NQO1, thus supporting our NMR data that the P187S variant exhibits a more disordered structure compared to that of NQO1\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/08/06
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A2
Stoichiometry for interactor B0
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant