| Unique identifier for interactor A | uniprotkb:P15692 |
| Unique identifier for interactor B | uniprotkb:P15692 |
| Alternative identifier for interactor A | intact:EBI-1026643 uniprotkb:B5BU86 uniprotkb:H0Y2S8 uniprotkb:H0Y407 uniprotkb:H0Y414 uniprotkb:H0Y462 uniprotkb:H0Y8N2 uniprotkb:H3BLW7 ensembl:ENSP00000500082.3 uniprotkb:O60720 uniprotkb:O75875 uniprotkb:Q074Z4 uniprotkb:Q16889 uniprotkb:Q5UB46 uniprotkb:Q6P0P5 uniprotkb:Q96KJ0 uniprotkb:Q96L82 uniprotkb:Q96NW5 uniprotkb:Q9H1W8 uniprotkb:Q9H1W9 uniprotkb:Q9UH58 uniprotkb:Q9UL23 |
| Alternative identifier for interactor B | intact:EBI-1026643 uniprotkb:B5BU86 uniprotkb:H0Y2S8 uniprotkb:H0Y407 uniprotkb:H0Y414 uniprotkb:H0Y462 uniprotkb:H0Y8N2 uniprotkb:H3BLW7 ensembl:ENSP00000500082.3 uniprotkb:O60720 uniprotkb:O75875 uniprotkb:Q074Z4 uniprotkb:Q16889 uniprotkb:Q5UB46 uniprotkb:Q6P0P5 uniprotkb:Q96KJ0 uniprotkb:Q96L82 uniprotkb:Q96NW5 uniprotkb:Q9H1W8 uniprotkb:Q9H1W9 uniprotkb:Q9UH58 uniprotkb:Q9UL23 |
| Aliases for A | psi-mi:vegfa_human(display_long) uniprotkb:Vascular permeability factor(gene name synonym) uniprotkb:VEGFA(gene name) psi-mi:VEGFA(display_short) uniprotkb:VEGF(gene name synonym) |
| Aliases for B | psi-mi:vegfa_human(display_long) uniprotkb:Vascular permeability factor(gene name synonym) uniprotkb:VEGFA(gene name) psi-mi:VEGFA(display_short) uniprotkb:VEGF(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0808"(comigration in sds page) |
| First author | Ghavamipour et al. (2014) |
| Identifier of the publication | imex:IM-23057 pubmed:25132001 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9683487 imex:IM-23057-1 |
| Confidence score | intact-miscore:0.72 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f5 comment:"\"We appraised whether the refolded constructs form dimer by reducing and non-reducing SDS-PAGE. The refolded WT VEGF, HD-VEGF and M-VEGF revealed 28 kDa bands at the expected position of dimeric VEGF RBD under non-reducing condition, whereas the same sample appeared at the position corresponded to monomer in reducing conditions (data not shown). These analyses confirmed that the refolded proteins are disulfide-linked dimer.\"" comment:"\"M-VEGF= Two most important segments of VEGF for KDR binding, including 41DEIEYI46 and 81 MRIKPHQ87, were replaced with segments 166GEGDEILT 173 and 42HGLRPSVA46 from two different x-ray crystallized proteins (PDB ID: 1XRH and 1SGL respectively).\"" full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/08/01 |
| Update date | 2023/07/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:188-289 his tag:?-? |
| Feature(s) for interactor B | strep tag:?-? binding-associated region:188-289 |
| Stoichiometry for interactor A | 2 |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Molecular weight estimation by coomasie staining |
| Participant identification method for interactor B | Molecular weight estimation by coomasie staining |