Curation Details
Interaction ID: IM-23055-2

Unique identifier for interactor Auniprotkb:Q9Y6D0
Unique identifier for interactor Buniprotkb:Q9Y6D0
Alternative identifier for interactor Aintact:EBI-9679163
uniprotkb:Q8IZQ3
uniprotkb:Q9P085
ensembl:ENSP00000418813.1
Alternative identifier for interactor Bintact:EBI-9679163
uniprotkb:Q8IZQ3
uniprotkb:Q9P085
ensembl:ENSP00000418813.1
Aliases for Apsi-mi:selk_human(display_long)
uniprotkb:SELENOK(gene name)
psi-mi:SELENOK(display_short)
uniprotkb:SELK(gene name synonym)
uniprotkb:HSPC030(orf name)
uniprotkb:HSPC297(orf name)
Aliases for Bpsi-mi:selk_human(display_long)
uniprotkb:SELENOK(gene name)
psi-mi:SELENOK(display_short)
uniprotkb:SELK(gene name synonym)
uniprotkb:HSPC030(orf name)
uniprotkb:HSPC297(orf name)
Interaction detection methodspsi-mi:"MI:0808"(comigration in sds page)
First authorLiu et al. (2014)
Identifier of the publicationimex:IM-23055
pubmed:25117454
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9679224
imex:IM-23055-2
Confidence scoreintact-miscore:0.56
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2a sf1
comment:"\"As can be observed from a SDS-PAGE run under non-reducing conditions (Fig. 2A), SelK U92 migrated as a dimer of 23 kDa, SelK U92C migrated mostly as a dimer, and SelK U92S migrated mostly as a monomer. All three proteins migrated as a monomer of 11.5 kDa under reducing conditions.\""
comment:"\"The dimerization is not exclusively dependent on the presence of a diselenide bond since SelK U92S, which has no intermolecular bond, can run as both a monomer and dimer on denaturing SDS-PAGE when its concentration is sufficiently high (Supplementary data, Fig. S1).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/07/23
Update date2024/11/30
negative Boolean valuefalse
Feature(s) for interactor Astrep tag:?-?
mutation disrupting interaction:92-92
Feature(s) for interactor Bstrep tag:?-?
mutation disrupting interaction:92-92
Stoichiometry for interactor A2
Stoichiometry for interactor B0
Participant identification method for interactor AMolecular weight estimation by coomasie staining
Participant identification method for interactor BMolecular weight estimation by coomasie staining