Curation Details
Interaction ID: IM-22955-15

Unique identifier for interactor Auniprotkb:Q9UBU9
Unique identifier for interactor Buniprotkb:Q9UKK6
Alternative identifier for interactor Aintact:EBI-398874
ensembl:ENSP00000294172.2
ensembl:ENSP00000436679.1
uniprotkb:Q99799
uniprotkb:Q9UQL2
uniprotkb:B4E269
Alternative identifier for interactor Bintact:EBI-301889
ensembl:ENSP00000254998.2
Aliases for Apsi-mi:nxf1_human(display_long)
uniprotkb:NXF1(gene name)
psi-mi:NXF1(display_short)
uniprotkb:TAP(gene name synonym)
uniprotkb:Tip-associating protein(gene name synonym)
uniprotkb:Tip-associated protein(gene name synonym)
uniprotkb:mRNA export factor TAP(gene name synonym)
Aliases for Bpsi-mi:nxt1_human(display_long)
uniprotkb:NXT1(gene name)
psi-mi:NXT1(display_short)
uniprotkb:Protein p15(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorChang et al. (2013)
Identifier of the publicationimex:IM-22955
pubmed:23299939
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9085098
imex:IM-22955-15
Confidence scoreintact-miscore:0.84
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role AUnspecified role
Experimental role BUnspecified role
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f4c
comment:"\"We investigated what impact Alyref had on the interaction of Chtop with Nxf1 (Figure 4C) and found that increasing amounts of GB1-Alyref bound to Nxf1, stimulated the interaction of FLAG-Chtop with Nxf1. In contrast, FLAGUif, which binds aa 1–198 of Nxf1, was efficiently displaced by Gb1-Alyref in this assay. Together, these data suggest that Alyref stimulates Chtop binding to Nxf1, though we have not observed a reciprocal stimulation of Alyref binding to Nxf1 by Chtop.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2014/01/08
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by coomasie staining
Participant identification method for interactor BPredetermined participant