Curation Details
Interaction ID: IM-22943-1

Unique identifier for interactor Auniprotkb:P10636
Unique identifier for interactor Buniprotkb:Q8N841
Alternative identifier for interactor Aintact:EBI-366182
uniprotkb:P18518
uniprotkb:Q14799
uniprotkb:Q15549
uniprotkb:Q15550
uniprotkb:Q15551
uniprotkb:Q1RMF6
uniprotkb:Q53YB1
uniprotkb:Q5CZI7
uniprotkb:Q5XWF0
uniprotkb:Q6QT54
uniprotkb:Q9UDJ3
uniprotkb:Q9UMH0
uniprotkb:Q9UQ96
ensembl:ENSP00000458742.1
Alternative identifier for interactor Bintact:EBI-9099113
uniprotkb:Q658K6
ensembl:ENSP00000377043.3
ensembl:ENSP00000399211.2
intact:EBI-28973582
uniprotkb:B4DZJ5
uniprotkb:C9J233
uniprotkb:Q24KB1
uniprotkb:Q24KB2
uniprotkb:Q24KB6
uniprotkb:Q24KF3
uniprotkb:Q24KJ5
uniprotkb:Q24KN7
uniprotkb:Q24KS9
uniprotkb:Q24KX1
uniprotkb:Q24L13
uniprotkb:Q24L55
uniprotkb:Q24L76
uniprotkb:Q8IYW6
uniprotkb:Q8NA62
Aliases for Apsi-mi:tau_human(display_long)
uniprotkb:MAPT(gene name)
psi-mi:MAPT(display_short)
uniprotkb:MTBT1(gene name synonym)
uniprotkb:TAU(gene name synonym)
uniprotkb:Neurofibrillary tangle protein(gene name synonym)
uniprotkb:Paired helical filament-tau(gene name synonym)
uniprotkb:MAPTL(gene name synonym)
Aliases for Bpsi-mi:ttll6_human(display_long)
uniprotkb:Protein polyglutamylase TTLL6(gene name synonym)
uniprotkb:TTLL6(gene name)
psi-mi:TTLL6(display_short)
uniprotkb:TTL.6(gene name synonym)
uniprotkb:Tubulin--tyrosine ligase-like protein 6(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorZempel et al. (2013)
Identifier of the publicationpubmed:24065130
imex:IM-22943
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-9099147
imex:IM-22943-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f7h1
comment:"\"Next, we tested whether Tau and TTLL6 could be co‐immunoprecipitated. TTLL6 could precipitate full‐length hTau40 and the N‐terminal half of Tau (construct K25, containing the proline‐rich domain without the inserts; Gustke et al, 1994), but not the C‐terminal half (construct K10; Figure 7H).\""
dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease
dataset:Neurodegeneration - Publications depicting interactions involved in neurodegenerative diseases.
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2014/01/27
Update date2024/01/27
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:1-244
ha tag:?-?
Feature(s) for interactor Byellow fluorescent protein tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot